YPEL5 protein (Homo sapiens) - STRING network view

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YPEL5

yippee-like 5 (Drosophila) (121 aa)

Predicted Functional Partners:

WDR26

0.847

UBC

0.737

RANBP10

0.607

MFSD9

0.598

ARHGAP28

0.577

PDCL3

0.564

FGF19

0.561

YIPF7

0.557

YIPF5

0.557

LCLAT1

0.551

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP28	LCLAT1	ENSP00000313506	ENSP00000310551	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	0.539
ARHGAP28	MFSD9	ENSP00000313506	ENSP00000258436	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	major facilitator superfamily domain containing 9	0.620
ARHGAP28	PDCL3	ENSP00000313506	ENSP00000264254	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	0.604
ARHGAP28	YPEL5	ENSP00000313506	ENSP00000261353	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	yippee-like 5 (Drosophila)	0.577
FGF19	YPEL5	ENSP00000294312	ENSP00000261353	fibroblast growth factor 19; Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4	yippee-like 5 (Drosophila)	0.561
LCLAT1	ARHGAP28	ENSP00000310551	ENSP00000313506	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	0.539
LCLAT1	MFSD9	ENSP00000310551	ENSP00000258436	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	major facilitator superfamily domain containing 9	0.545
LCLAT1	PDCL3	ENSP00000310551	ENSP00000264254	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	0.519
LCLAT1	UBC	ENSP00000310551	ENSP00000344818	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	ubiquitin C	0.738
LCLAT1	YPEL5	ENSP00000310551	ENSP00000261353	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	yippee-like 5 (Drosophila)	0.551
MFSD9	ARHGAP28	ENSP00000258436	ENSP00000313506	major facilitator superfamily domain containing 9	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	0.620
MFSD9	LCLAT1	ENSP00000258436	ENSP00000310551	major facilitator superfamily domain containing 9	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	0.545
MFSD9	PDCL3	ENSP00000258436	ENSP00000264254	major facilitator superfamily domain containing 9	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	0.615
MFSD9	YPEL5	ENSP00000258436	ENSP00000261353	major facilitator superfamily domain containing 9	yippee-like 5 (Drosophila)	0.598
PDCL3	ARHGAP28	ENSP00000264254	ENSP00000313506	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	Rho GTPase activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity)	0.604
PDCL3	LCLAT1	ENSP00000264254	ENSP00000310551	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	lysocardiolipin acyltransferase 1; Acyl-CoA-lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial [...]	0.519
PDCL3	MFSD9	ENSP00000264254	ENSP00000258436	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	major facilitator superfamily domain containing 9	0.615
PDCL3	UBC	ENSP00000264254	ENSP00000344818	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	ubiquitin C	0.634
PDCL3	YPEL5	ENSP00000264254	ENSP00000261353	phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination	yippee-like 5 (Drosophila)	0.564
RANBP10	UBC	ENSP00000316589	ENSP00000344818	RAN binding protein 10; Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase (By similarity). May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function (By similarity). May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen- induced transactivation. In contrast to RANBP9, does not interact with Sos [...]	ubiquitin C	0.776

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