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ABHD4 ABHD4 RGS2 RGS2 PRAF2 PRAF2 RGS16 RGS16 GDE1 GDE1 OAZ1 OAZ1 UBE2J2 UBE2J2 EXOC2 EXOC2 PPTC7 PPTC7 MAT2B MAT2B DSCR3 DSCR3
"GDE1" - glycerophosphodiester phosphodiesterase 1 in Homo sapiens
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protein of unknown 3D structure
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Score
GDE1glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity) (331 aa)    
Predicted Functional Partners:
RGS16
regulator of G-protein signaling 16; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade (202 aa)
        score_image   score_image   0.914
RGS2
regulator of G-protein signaling 2, 24kDa; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (211 aa)
        score_image   score_image   0.885
ABHD4
abhydrolase domain containing 4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lys [...] (342 aa)
            score_image   0.756
PRAF2
PRA1 domain family, member 2; May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis (178 aa)
            score_image   0.646
MAT2B
methionine adenosyltransferase II, beta (334 aa)
            score_image   0.640
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae) (304 aa)
            score_image   0.635
DSCR3
Down syndrome critical region gene 3 (297 aa)
            score_image   0.632
UBE2J2
ubiquitin-conjugating enzyme E2, J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity) (275 aa)
            score_image   0.622
EXOC2
exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane (924 aa)
            score_image   0.614
OAZ1
ornithine decarboxylase antizyme 1; Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (235 aa)
            score_image   0.597
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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