MRPS27 protein (Homo sapiens) - STRING network view

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Score

MRPS27

mitochondrial ribosomal protein S27 (414 aa)

Predicted Functional Partners:

DAP3

0.900

RIOK2

0.842

MRPS15

0.799

NOA1

0.799

MALSU1

0.769

MRPL12

0.753

MRPS18B

0.751

PTCD3

0.674

MRPL38

0.659

MRPS22

0.650

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAP3	MALSU1	ENSP00000341692	ENSP00000419370	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	0.474
DAP3	MRPS15	ENSP00000341692	ENSP00000362208	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S15	0.909
DAP3	MRPS18B	ENSP00000341692	ENSP00000259873	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S18B	0.779
DAP3	MRPS22	ENSP00000341692	ENSP00000310785	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S22	0.679
DAP3	MRPS27	ENSP00000341692	ENSP00000261413	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	mitochondrial ribosomal protein S27	0.900
DAP3	NOA1	ENSP00000341692	ENSP00000264230	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP	0.816
DAP3	PTCD3	ENSP00000341692	ENSP00000254630	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	pentatricopeptide repeat domain 3; Mitochondrial RNA-binding protein that has a role in mitochondrial translation	0.641
MALSU1	DAP3	ENSP00000419370	ENSP00000341692	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	0.474
MALSU1	MRPS18B	ENSP00000419370	ENSP00000259873	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	mitochondrial ribosomal protein S18B	0.648
MALSU1	MRPS22	ENSP00000419370	ENSP00000310785	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	mitochondrial ribosomal protein S22	0.714
MALSU1	MRPS27	ENSP00000419370	ENSP00000261413	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	mitochondrial ribosomal protein S27	0.769
MALSU1	NOA1	ENSP00000419370	ENSP00000264230	mitochondrial assembly of ribosomal large subunit 1; May function as a ribosomal silencing factor. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome	nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP	0.664
MRPL12	MRPS15	ENSP00000333837	ENSP00000362208	mitochondrial ribosomal protein L12	mitochondrial ribosomal protein S15	0.721
MRPL12	MRPS18B	ENSP00000333837	ENSP00000259873	mitochondrial ribosomal protein L12	mitochondrial ribosomal protein S18B	0.577
MRPL12	MRPS27	ENSP00000333837	ENSP00000261413	mitochondrial ribosomal protein L12	mitochondrial ribosomal protein S27	0.753
MRPL12	NOA1	ENSP00000333837	ENSP00000264230	mitochondrial ribosomal protein L12	nitric oxide associated 1; Involved in regulation of mitochondrial protein translation and respiration. Plays a role in mitochondria-mediated cell death. May act as a scaffolding protein or stabilizer of respiratory chain supercomplexes. Binds GTP	0.741
MRPL38	MRPS27	ENSP00000308275	ENSP00000261413	mitochondrial ribosomal protein L38	mitochondrial ribosomal protein S27	0.659
MRPS15	DAP3	ENSP00000362208	ENSP00000341692	mitochondrial ribosomal protein S15	death associated protein 3; Involved in mediating interferon-gamma-induced cell death	0.909
MRPS15	MRPL12	ENSP00000362208	ENSP00000333837	mitochondrial ribosomal protein S15	mitochondrial ribosomal protein L12	0.721
MRPS15	MRPS22	ENSP00000362208	ENSP00000310785	mitochondrial ribosomal protein S15	mitochondrial ribosomal protein S22	0.449

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