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STRINGSTRING
LSS LSS LBR LBR HSD17B7 HSD17B7 NSDHL NSDHL SC5DL SC5DL UBC UBC MSMO1 MSMO1 TM7SF2 TM7SF2 FDFT1 FDFT1 CYP51A1 CYP51A1 SQLE SQLE
"MSMO1" - methylsterol monooxygenase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
large protein node
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
MSMO1methylsterol monooxygenase 1 (293 aa)    
Predicted Functional Partners:
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7; Responsible for the reduction of the keto group on the C-3 of sterols (341 aa)
      score_image score_image score_image score_image   0.998
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1 (509 aa)
      score_image score_image   score_image   0.997
SQLE
squalene epoxidase; Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway (574 aa)
      score_image score_image   score_image   0.996
FDFT1
farnesyl-diphosphate farnesyltransferase 1 (417 aa)
    score_image score_image score_image   score_image   0.993
SC5DL
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol (299 aa)
    score_image score_image score_image   score_image score_image 0.988
LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus (732 aa)
      score_image score_image   score_image   0.987
UBC
ubiquitin C (685 aa)
        score_image       0.988
TM7SF2
transmembrane 7 superfamily member 2; Involved in the conversion of lanosterol to cholesterol (418 aa)
      score_image score_image score_image score_image   0.979
LBR
lamin B receptor; Anchors the lamina and the heterochromatin to the inner nuclear membrane (615 aa)
      score_image score_image score_image score_image   0.971
NSDHL
NAD(P) dependent steroid dehydrogenase-like (373 aa)
      score_image score_image   score_image   0.969
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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