node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AARS | ASNS | ENSP00000261772 | ENSP00000175506 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | asparagine synthetase (glutamine-hydrolyzing) | 0.983 |
AARS | DARS | ENSP00000261772 | ENSP00000264161 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA | 0.982 |
AARS | FARSB | ENSP00000261772 | ENSP00000281828 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | phenylalanyl-tRNA synthetase, beta subunit | 0.989 |
AARS | GARS | ENSP00000261772 | ENSP00000373918 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs | 0.998 |
AARS | IARS | ENSP00000261772 | ENSP00000364794 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | isoleucyl-tRNA synthetase | 0.995 |
AARS | LARS | ENSP00000261772 | ENSP00000377954 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | leucyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs | 0.998 |
AARS | MARS | ENSP00000261772 | ENSP00000262027 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | methionyl-tRNA synthetase | 0.968 |
AARS | NARS | ENSP00000261772 | ENSP00000256854 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | asparaginyl-tRNA synthetase | 0.996 |
AARS | QARS | ENSP00000261772 | ENSP00000307567 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | glutaminyl-tRNA synthetase | 0.992 |
AARS | UBA1 | ENSP00000261772 | ENSP00000338413 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | ubiquitin-like modifier activating enzyme 1; Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP | 0.974 |
ASNS | AARS | ENSP00000175506 | ENSP00000261772 | asparagine synthetase (glutamine-hydrolyzing) | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | 0.983 |
ASNS | DARS | ENSP00000175506 | ENSP00000264161 | asparagine synthetase (glutamine-hydrolyzing) | aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA | 0.568 |
ASNS | GARS | ENSP00000175506 | ENSP00000373918 | asparagine synthetase (glutamine-hydrolyzing) | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs | 0.989 |
ASNS | IARS | ENSP00000175506 | ENSP00000364794 | asparagine synthetase (glutamine-hydrolyzing) | isoleucyl-tRNA synthetase | 0.979 |
ASNS | MARS | ENSP00000175506 | ENSP00000262027 | asparagine synthetase (glutamine-hydrolyzing) | methionyl-tRNA synthetase | 0.407 |
ASNS | NARS | ENSP00000175506 | ENSP00000256854 | asparagine synthetase (glutamine-hydrolyzing) | asparaginyl-tRNA synthetase | 0.758 |
ASNS | QARS | ENSP00000175506 | ENSP00000307567 | asparagine synthetase (glutamine-hydrolyzing) | glutaminyl-tRNA synthetase | 0.522 |
DARS | AARS | ENSP00000264161 | ENSP00000261772 | aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | 0.982 |
DARS | ASNS | ENSP00000264161 | ENSP00000175506 | aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA | asparagine synthetase (glutamine-hydrolyzing) | 0.568 |
DARS | FARSB | ENSP00000264161 | ENSP00000281828 | aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA | phenylalanyl-tRNA synthetase, beta subunit | 0.621 |