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UBA1 UBA1 AARS AARS GARS GARS NARS NARS ASNS ASNS IARS IARS QARS QARS FARSB FARSB LARS LARS MARS MARS DARS DARS
"AARS" - alanyl-tRNA synthetase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
AARSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) (968 aa)    
Predicted Functional Partners:
GARS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs (739 aa)
      score_image score_image   score_image   0.998
LARS
leucyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs (1176 aa)
score_image     score_image score_image   score_image   0.998
NARS
asparaginyl-tRNA synthetase (548 aa)
score_image     score_image score_image   score_image   0.996
IARS
isoleucyl-tRNA synthetase (1262 aa)
score_image     score_image score_image   score_image   0.995
QARS
glutaminyl-tRNA synthetase (775 aa)
score_image     score_image score_image   score_image   0.992
FARSB
phenylalanyl-tRNA synthetase, beta subunit (589 aa)
      score_image score_image   score_image   0.989
ASNS
asparagine synthetase (glutamine-hydrolyzing) (561 aa)
      score_image score_image   score_image   0.983
DARS
aspartyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (501 aa)
score_image     score_image score_image   score_image   0.982
UBA1
ubiquitin-like modifier activating enzyme 1; Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin- E1 thioester and free AMP (1058 aa)
      score_image score_image   score_image   0.974
MARS
methionyl-tRNA synthetase (900 aa)
      score_image     score_image   0.968
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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