node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAGAB | ACP1 | ENSP00000261880 | ENSP00000272065 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | acid phosphatase 1, soluble; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity | 0.513 |
AAGAB | AP1S3 | ENSP00000261880 | ENSP00000379891 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | 0.613 |
AAGAB | AP2S1 | ENSP00000261880 | ENSP00000263270 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | adaptor-related protein complex 2, sigma 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as [...] | 0.613 |
AAGAB | BOD1 | ENSP00000261880 | ENSP00000309644 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | biorientation of chromosomes in cell division 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles | 0.539 |
AAGAB | DCAF13 | ENSP00000261880 | ENSP00000297579 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex | 0.474 |
AAGAB | HEATR1 | ENSP00000261880 | ENSP00000355541 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.557 |
AAGAB | KRT9 | ENSP00000261880 | ENSP00000246662 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | keratin 9; May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly | 0.561 |
AAGAB | PSD2 | ENSP00000261880 | ENSP00000274710 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | pleckstrin and Sec7 domain containing 2 | 0.472 |
AAGAB | UBC | ENSP00000261880 | ENSP00000344818 | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | ubiquitin C | 0.483 |
ACP1 | AAGAB | ENSP00000272065 | ENSP00000261880 | acid phosphatase 1, soluble; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.513 |
ACP1 | UBC | ENSP00000272065 | ENSP00000344818 | acid phosphatase 1, soluble; Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity | ubiquitin C | 0.765 |
AP1S3 | AAGAB | ENSP00000379891 | ENSP00000261880 | adaptor-related protein complex 1, sigma 3 subunit; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.613 |
AP2S1 | AAGAB | ENSP00000263270 | ENSP00000261880 | adaptor-related protein complex 2, sigma 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as [...] | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.613 |
AP2S1 | UBC | ENSP00000263270 | ENSP00000344818 | adaptor-related protein complex 2, sigma 1 subunit; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as [...] | ubiquitin C | 0.949 |
BOD1 | AAGAB | ENSP00000309644 | ENSP00000261880 | biorientation of chromosomes in cell division 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.539 |
BOD1 | DCAF13 | ENSP00000309644 | ENSP00000297579 | biorientation of chromosomes in cell division 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles | DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex | 0.431 |
BOD1 | UBC | ENSP00000309644 | ENSP00000344818 | biorientation of chromosomes in cell division 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles | ubiquitin C | 0.721 |
DCAF13 | AAGAB | ENSP00000297579 | ENSP00000261880 | DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex | alpha- and gamma-adaptin binding protein; May be involved in endocytic recycling of growth factor receptors such as EGFR | 0.474 |
DCAF13 | BOD1 | ENSP00000297579 | ENSP00000309644 | DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex | biorientation of chromosomes in cell division 1; Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles | 0.431 |
DCAF13 | HEATR1 | ENSP00000297579 | ENSP00000355541 | DDB1 and CUL4 associated factor 13; Possible role in ribosomal RNA processing (By similarity). May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.990 |