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STRINGSTRING
INTS9 INTS9 GAS7 GAS7 CPSF3L CPSF3L ATP13A1 ATP13A1 ANKRD26 ANKRD26 LACTB LACTB PPM1L PPM1L ABHD13 ABHD13 LPL LPL MRPS27 MRPS27 MRPS36 MRPS36
"LACTB" - lactamase, beta in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
LACTBlactamase, beta (547 aa)    
Predicted Functional Partners:
INTS9
integrator complex subunit 9; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (658 aa)
             score_image   0.755
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L; Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6 (360 aa)
             score_image   0.749
CPSF3L
cleavage and polyadenylation specific factor 3-like (600 aa)
             score_image   0.680
LPL
lipoprotein lipase; The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity) (475 aa)
             score_image   0.659
MRPS36
mitochondrial ribosomal protein S36 (103 aa)
             score_image   0.655
MRPS27
mitochondrial ribosomal protein S27 (414 aa)
             score_image   0.642
ABHD13
abhydrolase domain containing 13 (337 aa)
             score_image   0.610
GAS7
growth arrest-specific 7; May play a role in promoting maturation and morphological differentiation of cerebellar neurons (476 aa)
             score_image   0.609
ANKRD26
ankyrin repeat domain 26 (1710 aa)
             score_image   0.606
ATP13A1
ATPase type 13A1 (1204 aa)
             score_image   0.606
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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