| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDHR2 | CDHR5 | ENSP00000261944 | ENSP00000351118 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | cadherin-related family member 5 | 0.760 |
| CDHR2 | CLDN17 | ENSP00000261944 | ENSP00000286808 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | 0.420 |
| CDHR2 | MAST2 | ENSP00000261944 | ENSP00000354671 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | microtubule associated serine/threonine kinase 2; Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity) | 0.711 |
| CDHR2 | MYO7B | ENSP00000261944 | ENSP00000386461 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | 0.587 |
| CDHR2 | NSD1 | ENSP00000261944 | ENSP00000395929 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | nuclear receptor binding SET domain protein 1; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context | 0.471 |
| CDHR2 | RAB24 | ENSP00000261944 | ENSP00000304376 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | RAB24, member RAS oncogene family; May be involved in autophagy-related processes (By similarity) | 0.562 |
| CDHR2 | USH1C | ENSP00000261944 | ENSP00000005226 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | 0.655 |
| CDHR5 | CDHR2 | ENSP00000351118 | ENSP00000261944 | cadherin-related family member 5 | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.760 |
| CDHR5 | MYO7B | ENSP00000351118 | ENSP00000386461 | cadherin-related family member 5 | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | 0.634 |
| CDHR5 | USH1C | ENSP00000351118 | ENSP00000005226 | cadherin-related family member 5 | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | 0.679 |
| CLDN17 | CDHR2 | ENSP00000286808 | ENSP00000261944 | claudin 17; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity) | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.420 |
| MAST2 | CDHR2 | ENSP00000354671 | ENSP00000261944 | microtubule associated serine/threonine kinase 2; Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity) | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.711 |
| MYO7B | CDHR2 | ENSP00000386461 | ENSP00000261944 | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.587 |
| MYO7B | CDHR5 | ENSP00000386461 | ENSP00000351118 | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | cadherin-related family member 5 | 0.634 |
| MYO7B | USH1C | ENSP00000386461 | ENSP00000005226 | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | 0.642 |
| NSD1 | CDHR2 | ENSP00000395929 | ENSP00000261944 | nuclear receptor binding SET domain protein 1; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.471 |
| RAB24 | CDHR2 | ENSP00000304376 | ENSP00000261944 | RAB24, member RAS oncogene family; May be involved in autophagy-related processes (By similarity) | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.562 |
| USH1C | CDHR2 | ENSP00000005226 | ENSP00000261944 | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | cadherin-related family member 2; Role in contact inhibition at the lateral surface of epithelial cells | 0.655 |
| USH1C | CDHR5 | ENSP00000005226 | ENSP00000351118 | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | cadherin-related family member 5 | 0.679 |
| USH1C | MYO7B | ENSP00000005226 | ENSP00000386461 | Usher syndrome 1C (autosomal recessive, severe); Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity) | myosin VIIB; Myosins are actin-based motor molecules with ATPase activity. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be have a role in the apical membranes of transporting epithelia (By similarity) | 0.642 |
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