| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AS3MT | MMD | ENSP00000358896 | ENSP00000262065 | arsenic (+3 oxidation state) methyltransferase; Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity) | monocyte to macrophage differentiation-associated; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion (By similarity) | 0.860 |
| CD320 | LMBRD1 | ENSP00000301458 | ENSP00000359609 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | 0.742 |
| CD320 | MMAA | ENSP00000301458 | ENSP00000281317 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | 0.687 |
| CD320 | MMAB | ENSP00000301458 | ENSP00000445920 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.689 |
| CD320 | MMADHC | ENSP00000301458 | ENSP00000301920 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria; Involved in cobalamin metabolism | 0.714 |
| CD320 | MMD | ENSP00000301458 | ENSP00000262065 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | monocyte to macrophage differentiation-associated; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion (By similarity) | 0.750 |
| CD320 | MUT | ENSP00000301458 | ENSP00000274813 | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species | 0.658 |
| GSTA1 | MMD | ENSP00000335620 | ENSP00000262065 | glutathione S-transferase alpha 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles | monocyte to macrophage differentiation-associated; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion (By similarity) | 0.818 |
| LMBRD1 | CD320 | ENSP00000359609 | ENSP00000301458 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | 0.742 |
| LMBRD1 | MMAA | ENSP00000359609 | ENSP00000281317 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | 0.860 |
| LMBRD1 | MMAB | ENSP00000359609 | ENSP00000445920 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.860 |
| LMBRD1 | MMADHC | ENSP00000359609 | ENSP00000301920 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria; Involved in cobalamin metabolism | 0.885 |
| LMBRD1 | MMD | ENSP00000359609 | ENSP00000262065 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | monocyte to macrophage differentiation-associated; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion (By similarity) | 0.750 |
| LMBRD1 | MUT | ENSP00000359609 | ENSP00000274813 | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species | 0.860 |
| MMAA | CD320 | ENSP00000281317 | ENSP00000301458 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | CD320 molecule; Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin | 0.687 |
| MMAA | LMBRD1 | ENSP00000281317 | ENSP00000359609 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | LMBR1 domain containing 1; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV) | 0.860 |
| MMAA | MMAB | ENSP00000281317 | ENSP00000445920 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.991 |
| MMAA | MMADHC | ENSP00000281317 | ENSP00000301920 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria; Involved in cobalamin metabolism | 0.860 |
| MMAA | MMD | ENSP00000281317 | ENSP00000262065 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | monocyte to macrophage differentiation-associated; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion (By similarity) | 0.808 |
| MMAA | MUT | ENSP00000281317 | ENSP00000274813 | methylmalonic aciduria (cobalamin deficiency) cblA type; Probable GTPase. May function as chaperone. May be involved in the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis | methylmalonyl CoA mutase; Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species | 0.999 |
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