Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | TSPAN13 | tetraspanin 13 (204 aa) | ||||||||||||
Predicted Functional Partners:
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 | TSPAN15 | tetraspanin 15 (294 aa) |
 |
0.686 | ||||||||||
 | ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) (798 aa) |
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0.660 | ||||||||||
 | TSPAN9 | tetraspanin 9 (239 aa) |
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0.645 | ||||||||||
 | TSPAN18 | tetraspanin 18 (248 aa) |
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0.639 | ||||||||||
 | TSPAN4 | tetraspanin 4 (238 aa) |
|
0.617 | ||||||||||
 | TSPAN1 | tetraspanin 1 (241 aa) |
|
0.592 | ||||||||||
 | FAM159B | family with sequence similarity 159, member B (160 aa) |
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0.585 | ||||||||||
 | TSPAN8 | tetraspanin 8 (237 aa) |
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0.535 | ||||||||||
 | ANXA13 | annexin A13 (357 aa) |
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0.523 | ||||||||||
 | TSPAN33 | tetraspanin 33; Plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors (By similarity) (283 aa) |
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0.518 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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