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STRINGSTRING
PPP6R1 PPP6R1 TTC23 TTC23 C1orf173 C1orf173 CCDC66 CCDC66 SLC45A4 SLC45A4
"TTC23" - tetratricopeptide repeat domain 23 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC23tetratricopeptide repeat domain 23 (447 aa)    
Predicted Functional Partners:
C1orf173
chromosome 1 open reading frame 173 (1530 aa)
            score_image   0.721
SLC45A4
solute carrier family 45, member 4 (798 aa)
            score_image   0.539
CCDC66
coiled-coil domain containing 66 (948 aa)
            score_image   0.459
PPP6R1
protein phosphatase 6, regulatory subunit 1; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha (881 aa)
            score_image   0.404
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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