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REM1 REM1 DDX21 DDX21 PHB2 PHB2 CKAP4 CKAP4 GOLGA7 GOLGA7 ZDHHC2 ZDHHC2 ARMC4 ARMC4 RTDR1 RTDR1 MTMR7 MTMR7 CNOT7 CNOT7 VPS37A VPS37A
"ZDHHC2" - zinc finger, DHHC-type containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZDHHC2zinc finger, DHHC-type containing 2; Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity) (367 aa)    
Predicted Functional Partners:
CKAP4
cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF (602 aa)
            score_image   0.876
ARMC4
armadillo repeat containing 4 (1044 aa)
        score_image   score_image   0.854
RTDR1
rhabdoid tumor deletion region gene 1 (348 aa)
        score_image   score_image   0.820
VPS37A
vacuolar protein sorting 37 homolog A (S. cerevisiae); Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (397 aa)
            score_image   0.660
PHB2
prohibitin 2; Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (299 aa)
            score_image   0.581
CNOT7
CCR4-NOT transcription complex, subunit 7; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translation [...] (285 aa)
            score_image   0.514
MTMR7
myotubularin related protein 7; Phosphatase that acts on lipids with a phosphoinositol headgroup (Probable) (660 aa)
            score_image   0.507
GOLGA7
golgin A7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (137 aa)
            score_image   0.472
DDX21
DEAD (Asp-Glu-Ala-Asp) box helicase 21; Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing (783 aa)
            score_image   0.459
REM1
RAS (RAD and GEM)-like GTP-binding 1; Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling (298 aa)
        score_image   score_image   0.453
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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