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RAB11FIP2 RAB11FIP2 RAB11FIP5 RAB11FIP5 EXOC7 EXOC7 RAB11B RAB11B RAB25 RAB25 RAB11A RAB11A ARF6 ARF6 RAB11FIP3 RAB11FIP3 ARF5 ARF5 KIF23 KIF23 PI4KB PI4KB
"RAB11FIP3" - RAB11 family interacting protein 3 (class II) in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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RAB11FIP3RAB11 family interacting protein 3 (class II) (756 aa)    
Predicted Functional Partners:
RAB11A
RAB11A, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polariza [...] (216 aa)
        score_image score_image score_image   0.999
ARF6
ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development (By similarity). Contributes to the regulation of dendritic branching and filopodia extension (175 aa)
        score_image score_image score_image   0.996
RAB11B
RAB11B, member RAS oncogene family; GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis (By similarity) (218 aa)
        score_image score_image score_image   0.989
RAB25
RAB25, member RAS oncogene family; Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Increases the rates of ovarian and breast cancers progression and aggressiveness by modulating cellular processes such as proliferation, survival and migration of epithelial tumor cells. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity) (213 aa)
        score_image   score_image   0.979
RAB11FIP5
RAB11 family interacting protein 5 (class I); Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane (653 aa)
            score_image   0.948
ARF5
ADP-ribosylation factor 5; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (180 aa)
        score_image   score_image   0.936
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity) (828 aa)
        score_image   score_image   0.904
EXOC7
exocyst complex component 7 (735 aa)
            score_image   0.866
KIF23
kinesin family member 23; Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro (960 aa)
        score_image   score_image   0.823
RAB11FIP2
RAB11 family interacting protein 2 (class I); A Rab11 effector protein acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA). Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity (512 aa)
            score_image   0.818
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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