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GLIS3 GLIS3 RTN2 RTN2 NFE2L2 NFE2L2 GLUL GLUL SLC6A1 SLC6A1 SLC1A1 SLC1A1 RFX1 RFX1 ADCY6 ADCY6 ARL6IP5 ARL6IP5 PAIP2B PAIP2B ATP1B3 ATP1B3
"SLC1A1" - solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 in Homo sapiens
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protein of unknown 3D structure
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SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5 (By similarity) (524 aa)    
Predicted Functional Partners:
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5; Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By similarity) (188 aa)
        score_image   score_image   0.983
RFX1
regulatory factor X, 1 (influences HLA class II expression); Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter (979 aa)
            score_image   0.899
NFE2L2
nuclear factor (erythroid-derived 2)-like 2; Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region (605 aa)
            score_image   0.820
RTN2
reticulon 2 (545 aa)
            score_image   0.788
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals (599 aa)
      score_image     score_image   0.761
PAIP2B
poly(A) binding protein interacting protein 2B (123 aa)
            score_image   0.751
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known (279 aa)
            score_image   0.750
ADCY6
adenylate cyclase 6; Membrane-bound, calcium-inhibitable adenylyl cyclase (By similarity) (1168 aa)
            score_image   0.688
GLUL
glutamate-ammonia ligase; This enzyme has 2 functions- it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts (373 aa)
            score_image   0.674
GLIS3
GLIS family zinc finger 3; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5’-GACCACCCAC-3’ (By similarity) (930 aa)
            score_image   0.655
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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