node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLZF1 | GOLGA2 | ENSP00000327541 | ENSP00000416097 | basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | 0.414 |
BLZF1 | GORASP2 | ENSP00000327541 | ENSP00000234160 | basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | golgi reassembly stacking protein 2, 55kDa; Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA | 0.999 |
BLZF1 | RAB2A | ENSP00000327541 | ENSP00000262646 | basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.998 |
BLZF1 | UBC | ENSP00000327541 | ENSP00000344818 | basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | ubiquitin C | 0.483 |
ERLIN2 | FLOT2 | ENSP00000276461 | ENSP00000378368 | ER lipid raft associated 2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway | flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function | 0.949 |
ERLIN2 | RAB2A | ENSP00000276461 | ENSP00000262646 | ER lipid raft associated 2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.960 |
ERLIN2 | UBC | ENSP00000276461 | ENSP00000344818 | ER lipid raft associated 2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway | ubiquitin C | 0.919 |
FLOT2 | ERLIN2 | ENSP00000378368 | ENSP00000276461 | flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function | ER lipid raft associated 2; Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway | 0.949 |
FLOT2 | RAB2A | ENSP00000378368 | ENSP00000262646 | flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.903 |
FLOT2 | UBC | ENSP00000378368 | ENSP00000344818 | flotillin 2; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function | ubiquitin C | 0.897 |
GAPDH | RAB2A | ENSP00000229239 | ENSP00000262646 | glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations throu [...] | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.967 |
GAPDH | SLC2A4 | ENSP00000229239 | ENSP00000320935 | glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations throu [...] | solute carrier family 2 (facilitated glucose transporter), member 4; Insulin-regulated facilitative glucose transporter | 0.929 |
GAPDH | UBC | ENSP00000229239 | ENSP00000344818 | glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations throu [...] | ubiquitin C | 0.999 |
GOLGA2 | BLZF1 | ENSP00000416097 | ENSP00000327541 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | basic leucine zipper nuclear factor 1; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | 0.414 |
GOLGA2 | GOLGA4 | ENSP00000416097 | ENSP00000349305 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | golgin A4; May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 | 0.580 |
GOLGA2 | GORASP2 | ENSP00000416097 | ENSP00000234160 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | golgi reassembly stacking protein 2, 55kDa; Plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA | 0.976 |
GOLGA2 | RAB2A | ENSP00000416097 | ENSP00000262646 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.827 |
GOLGA2 | UBC | ENSP00000416097 | ENSP00000344818 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | ubiquitin C | 0.730 |
GOLGA4 | GOLGA2 | ENSP00000349305 | ENSP00000416097 | golgin A4; May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure | 0.580 |
GOLGA4 | RAB2A | ENSP00000349305 | ENSP00000262646 | golgin A4; May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1 | RAB2A, member RAS oncogene family; Required for protein transport from the endoplasmic reticulum to the Golgi complex | 0.834 |