LGALS3BP protein (Homo sapiens) - STRING network view

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LGALS3BP

lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells (585 aa)

Predicted Functional Partners:

LGALS3

0.998

CST4

0.801

LGALS1

0.779

SP2

0.760

UBC

0.741

CD248

0.661

PPIC

0.657

SYNCRIP

0.656

NID1

0.653

FN1

0.629

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD248	LGALS3BP	ENSP00000308117	ENSP00000262776	CD248 molecule, endosialin; May play a role in tumor angiogenesis	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	0.661
CST4	LGALS3	ENSP00000217423	ENSP00000254301	cystatin S; This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	0.814
CST4	LGALS3BP	ENSP00000217423	ENSP00000262776	cystatin S; This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	0.801
FN1	LGALS3	ENSP00000346839	ENSP00000254301	fibronectin 1	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	0.414
FN1	LGALS3BP	ENSP00000346839	ENSP00000262776	fibronectin 1	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	0.629
FN1	NID1	ENSP00000346839	ENSP00000264187	fibronectin 1	nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions	0.614
FN1	UBC	ENSP00000346839	ENSP00000344818	fibronectin 1	ubiquitin C	0.810
LGALS1	LGALS3	ENSP00000215909	ENSP00000254301	lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	0.653
LGALS1	LGALS3BP	ENSP00000215909	ENSP00000262776	lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	0.779
LGALS1	UBC	ENSP00000215909	ENSP00000344818	lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase	ubiquitin C	0.903
LGALS3	CST4	ENSP00000254301	ENSP00000217423	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	cystatin S; This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively	0.814
LGALS3	FN1	ENSP00000254301	ENSP00000346839	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	fibronectin 1	0.414
LGALS3	LGALS1	ENSP00000254301	ENSP00000215909	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase	0.653
LGALS3	LGALS3BP	ENSP00000254301	ENSP00000262776	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	0.998
LGALS3	SP2	ENSP00000254301	ENSP00000365931	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	Sp2 transcription factor; Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites	0.400
LGALS3BP	CD248	ENSP00000262776	ENSP00000308117	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	CD248 molecule, endosialin; May play a role in tumor angiogenesis	0.661
LGALS3BP	CST4	ENSP00000262776	ENSP00000217423	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	cystatin S; This protein strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively	0.801
LGALS3BP	FN1	ENSP00000262776	ENSP00000346839	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	fibronectin 1	0.629
LGALS3BP	LGALS1	ENSP00000262776	ENSP00000215909	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	lectin, galactoside-binding, soluble, 1; May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase	0.779
LGALS3BP	LGALS3	ENSP00000262776	ENSP00000254301	lectin, galactoside-binding, soluble, 3 binding protein; Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells	lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus- acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells	0.998

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