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WBSCR22 WBSCR22 HNRPLL HNRPLL FAM149B1 FAM149B1 RBM34 RBM34 YARS YARS HNRNPL HNRNPL METTL16 METTL16 SGSM2 SGSM2 RIMS2 RIMS2 MEPCE MEPCE DCP1B DCP1B
"METTL16" - methyltransferase like 16 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METTL16methyltransferase like 16; Probable methyltransferase (By similarity) (562 aa)    
Predicted Functional Partners:
RBM34
RNA binding motif protein 34 (430 aa)
            score_image   0.663
YARS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) (528 aa)
        score_image       0.644
MEPCE
methylphosphate capping enzyme; S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5’-end of 7SK snRNA, leading to stabilize it (689 aa)
        score_image   score_image   0.570
SGSM2
small G protein signaling modulator 2 (1051 aa)
            score_image   0.564
HNRNPL
heterogeneous nuclear ribonucleoprotein L; This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Is associated with most nascent transcripts including those of the landmark giant loops of amphibian lampbrush chromosomes. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (589 aa)
            score_image   0.512
FAM149B1
family with sequence similarity 149, member B1 (582 aa)
            score_image   0.485
WBSCR22
Williams Beuren syndrome chromosome region 22 (298 aa)
            score_image   0.461
HNRPLL
heterogeneous nuclear ribonucleoprotein L-like; RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC (537 aa)
            score_image   0.444
DCP1B
DCP1 decapping enzyme homolog B (S. cerevisiae); May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5’-phosphorylated mRNA fragment and 7m-GDP (By similarity) (617 aa)
            score_image   0.434
RIMS2
regulating synaptic membrane exocytosis 2; Rab effector involved in exocytosis. May act as scaffold protein (1349 aa)
            score_image   0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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