node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DGCR14 | DGCR2 | ENSP00000252137 | ENSP00000263196 | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | 0.760 |
DGCR14 | TBX1 | ENSP00000252137 | ENSP00000331791 | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.583 |
DGCR14 | UFD1L | ENSP00000252137 | ENSP00000263202 | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.741 |
DGCR2 | DGCR14 | ENSP00000263196 | ENSP00000252137 | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | 0.760 |
DGCR2 | DGCR6 | ENSP00000263196 | ENSP00000331681 | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.668 |
DGCR2 | TBX1 | ENSP00000263196 | ENSP00000331791 | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.681 |
DGCR2 | UFD1L | ENSP00000263196 | ENSP00000263202 | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.511 |
DGCR2 | ZNF74 | ENSP00000263196 | ENSP00000349098 | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | zinc finger protein 74 | 0.664 |
DGCR6 | DGCR2 | ENSP00000331681 | ENSP00000263196 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | 0.668 |
DGCR6 | TBX1 | ENSP00000331681 | ENSP00000331791 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | 0.589 |
DGCR6 | UFD1L | ENSP00000331681 | ENSP00000263202 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.732 |
DGCR6 | ZNF74 | ENSP00000331681 | ENSP00000349098 | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | zinc finger protein 74 | 0.662 |
TBX1 | DGCR14 | ENSP00000331791 | ENSP00000252137 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | 0.583 |
TBX1 | DGCR2 | ENSP00000331791 | ENSP00000263196 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | 0.681 |
TBX1 | DGCR6 | ENSP00000331791 | ENSP00000331681 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.589 |
TBX1 | UFD1L | ENSP00000331791 | ENSP00000263202 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | 0.514 |
TBX1 | ZNF74 | ENSP00000331791 | ENSP00000349098 | T-box 1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries (By similarity) | zinc finger protein 74 | 0.416 |
UFD1L | DGCR14 | ENSP00000263202 | ENSP00000252137 | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | DiGeorge syndrome critical region gene 14; May be involved in pre-mRNA splicing | 0.741 |
UFD1L | DGCR2 | ENSP00000263202 | ENSP00000263196 | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | DiGeorge syndrome critical region gene 2; Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration | 0.511 |
UFD1L | DGCR6 | ENSP00000263202 | ENSP00000331681 | ubiquitin fusion degradation 1 like (yeast); Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures | DiGeorge syndrome critical region gene 6; May play a role in neural crest cell migration into the third and fourth pharyngeal pouches | 0.732 |