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STRINGSTRING
C12orf55 C12orf55 NTF3 NTF3 RPGRIP1L RPGRIP1L POU4F2 POU4F2 BARHL1 BARHL1 INPP5E INPP5E ATOH1 ATOH1 POU4F1 POU4F1 LHX9 LHX9 POU4F3 POU4F3 MED7 MED7
"BARHL1" - BarH-like homeobox 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BARHL1BarH-like homeobox 1 (327 aa)    
Predicted Functional Partners:
NTF3
neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons (270 aa)
            score_image   0.873
POU4F3
POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons (338 aa)
            score_image   0.724
INPP5E
inositol polyphosphate-5-phosphatase, 72 kDa; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates (644 aa)
            score_image   0.683
LHX9
LIM homeobox 9; Involved in gonadal development (By similarity) (397 aa)
      score_image score_image   score_image   0.633
ATOH1
atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) (354 aa)
            score_image   0.591
POU4F1
POU class 4 homeobox 1; Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons (419 aa)
            score_image   0.549
POU4F2
POU class 4 homeobox 2; Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons (409 aa)
            score_image   0.520
RPGRIP1L
RPGRIP1-like; Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity) (1315 aa)
            score_image   0.519
MED7
mediator complex subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (233 aa)
        score_image       0.517
C12orf55
chromosome 12 open reading frame 55 (3096 aa)
            score_image   0.483
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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