node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATOH1 | BARHL1 | ENSP00000302216 | ENSP00000263610 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | BarH-like homeobox 1 | 0.591 |
ATOH1 | LHX9 | ENSP00000302216 | ENSP00000356357 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | LIM homeobox 9; Involved in gonadal development (By similarity) | 0.507 |
ATOH1 | POU4F1 | ENSP00000302216 | ENSP00000366413 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | POU class 4 homeobox 1; Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.698 |
ATOH1 | POU4F2 | ENSP00000302216 | ENSP00000281321 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | POU class 4 homeobox 2; Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.873 |
ATOH1 | POU4F3 | ENSP00000302216 | ENSP00000230732 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.626 |
BARHL1 | ATOH1 | ENSP00000263610 | ENSP00000302216 | BarH-like homeobox 1 | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | 0.591 |
BARHL1 | C12orf55 | ENSP00000263610 | ENSP00000431759 | BarH-like homeobox 1 | chromosome 12 open reading frame 55 | 0.483 |
BARHL1 | INPP5E | ENSP00000263610 | ENSP00000360777 | BarH-like homeobox 1 | inositol polyphosphate-5-phosphatase, 72 kDa; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates | 0.683 |
BARHL1 | LHX9 | ENSP00000263610 | ENSP00000356357 | BarH-like homeobox 1 | LIM homeobox 9; Involved in gonadal development (By similarity) | 0.633 |
BARHL1 | MED7 | ENSP00000263610 | ENSP00000286317 | BarH-like homeobox 1 | mediator complex subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors | 0.517 |
BARHL1 | NTF3 | ENSP00000263610 | ENSP00000397297 | BarH-like homeobox 1 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | 0.873 |
BARHL1 | POU4F1 | ENSP00000263610 | ENSP00000366413 | BarH-like homeobox 1 | POU class 4 homeobox 1; Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.549 |
BARHL1 | POU4F2 | ENSP00000263610 | ENSP00000281321 | BarH-like homeobox 1 | POU class 4 homeobox 2; Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.520 |
BARHL1 | POU4F3 | ENSP00000263610 | ENSP00000230732 | BarH-like homeobox 1 | POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons | 0.724 |
BARHL1 | RPGRIP1L | ENSP00000263610 | ENSP00000369257 | BarH-like homeobox 1 | RPGRIP1-like; Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity) | 0.519 |
C12orf55 | BARHL1 | ENSP00000431759 | ENSP00000263610 | chromosome 12 open reading frame 55 | BarH-like homeobox 1 | 0.483 |
INPP5E | BARHL1 | ENSP00000360777 | ENSP00000263610 | inositol polyphosphate-5-phosphatase, 72 kDa; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates | BarH-like homeobox 1 | 0.683 |
INPP5E | RPGRIP1L | ENSP00000360777 | ENSP00000369257 | inositol polyphosphate-5-phosphatase, 72 kDa; Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates | RPGRIP1-like; Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis (By similarity). Involved in the organization of apical junctions in kidney cells together with NPHP1 and NPHP4 (By similarity). Does not seem to be strictly required for ciliogenesis (By similarity) | 0.562 |
LHX9 | ATOH1 | ENSP00000356357 | ENSP00000302216 | LIM homeobox 9; Involved in gonadal development (By similarity) | atonal homolog 1 (Drosophila); Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity) | 0.507 |
LHX9 | BARHL1 | ENSP00000356357 | ENSP00000263610 | LIM homeobox 9; Involved in gonadal development (By similarity) | BarH-like homeobox 1 | 0.633 |