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SMCR8 SMCR8 ZNF786 ZNF786 COQ9 COQ9 COQ10B COQ10B ERLEC1 ERLEC1 COQ6 COQ6 ADCK3 ADCK3 COQ7 COQ7 ZNF425 ZNF425 ADCK4 ADCK4 COQ2 COQ2
"COQ10B" - coenzyme Q10 homolog B (S. cerevisiae) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
COQ10Bcoenzyme Q10 homolog B (S. cerevisiae); Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity) (238 aa)    
Predicted Functional Partners:
ADCK3
aarF domain containing kinase 3; May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain (647 aa)
        score_image   score_image   0.828
ADCK4
aarF domain containing kinase 4; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (544 aa)
        score_image   score_image   0.828
ZNF786
zinc finger protein 786; May be involved in transcriptional regulation (782 aa)
            score_image   0.679
COQ2
coenzyme Q2 homolog, prenyltransferase (yeast); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB (421 aa)
        score_image   score_image   0.666
ERLEC1
endoplasmic reticulum lectin 1; Probable lectin that binds selectively to improperly folded lumenal proteins. May function in endoplasmic reticulum quality control and endoplasmic reticulum-associated degradation (ERAD) of both non-glycosylated proteins and glycoproteins (483 aa)
            score_image   0.607
COQ7
coenzyme Q7 homolog, ubiquinone (yeast); Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator (By similarity) (217 aa)
        score_image   score_image   0.602
ZNF425
zinc finger protein 425; Acts as a transcriptional repressor (752 aa)
            score_image   0.588
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8 (937 aa)
            score_image   0.587
COQ6
coenzyme Q6 homolog, monooxygenase (S. cerevisiae) (468 aa)
    score_image       score_image   0.587
COQ9
coenzyme Q9 homolog (S. cerevisiae); Involved in the biosynthesis of coenzyme Q (By similarity) (318 aa)
            score_image   0.571
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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