TREH protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Known Interactions

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Score

TREH

trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose (582 aa)

Predicted Functional Partners:

LCT

0.828

DNAJB1

0.784

ATHL1

0.782

DNAJB5

0.727

DNAJB4

0.727

DNAJB13

0.727

MECR

0.719

TSPO

0.719

PGM1

0.714

PGM5

0.706

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATHL1	TREH	ENSP00000387185	ENSP00000264029	ATH1, acid trehalase-like 1 (yeast)	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.782
DNAJB1	PGM1	ENSP00000254322	ENSP00000360124	DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP	phosphoglucomutase 1	0.519
DNAJB1	PGM5	ENSP00000254322	ENSP00000379678	DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP	phosphoglucomutase 5	0.519
DNAJB1	TREH	ENSP00000254322	ENSP00000264029	DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.784
DNAJB1	TSPO	ENSP00000254322	ENSP00000328973	DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.414
DNAJB13	PGM1	ENSP00000344431	ENSP00000360124	DnaJ (Hsp40) homolog, subfamily B, member 13; May be involved in inhibiting testis spermatogenesis apoptosis	phosphoglucomutase 1	0.519
DNAJB13	PGM5	ENSP00000344431	ENSP00000379678	DnaJ (Hsp40) homolog, subfamily B, member 13; May be involved in inhibiting testis spermatogenesis apoptosis	phosphoglucomutase 5	0.519
DNAJB13	TREH	ENSP00000344431	ENSP00000264029	DnaJ (Hsp40) homolog, subfamily B, member 13; May be involved in inhibiting testis spermatogenesis apoptosis	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.727
DNAJB4	PGM1	ENSP00000359799	ENSP00000360124	DnaJ (Hsp40) homolog, subfamily B, member 4; Probable chaperone	phosphoglucomutase 1	0.519
DNAJB4	PGM5	ENSP00000359799	ENSP00000379678	DnaJ (Hsp40) homolog, subfamily B, member 4; Probable chaperone	phosphoglucomutase 5	0.519
DNAJB4	TREH	ENSP00000359799	ENSP00000264029	DnaJ (Hsp40) homolog, subfamily B, member 4; Probable chaperone	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.727
DNAJB5	PGM1	ENSP00000404079	ENSP00000360124	DnaJ (Hsp40) homolog, subfamily B, member 5	phosphoglucomutase 1	0.534
DNAJB5	PGM5	ENSP00000404079	ENSP00000379678	DnaJ (Hsp40) homolog, subfamily B, member 5	phosphoglucomutase 5	0.519
DNAJB5	TREH	ENSP00000404079	ENSP00000264029	DnaJ (Hsp40) homolog, subfamily B, member 5	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.727
LCT	TREH	ENSP00000264162	ENSP00000264029	lactase; LPH splits lactose in the small intestine	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.828
LCT	TSPO	ENSP00000264162	ENSP00000328973	lactase; LPH splits lactose in the small intestine	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.469
MECR	TREH	ENSP00000263702	ENSP00000264029	mitochondrial trans-2-enoyl-CoA reductase; Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids	trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose	0.719
MECR	TSPO	ENSP00000263702	ENSP00000328973	mitochondrial trans-2-enoyl-CoA reductase; Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids	translocator protein (18kDa); Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells (By similarity)	0.658
PGM1	DNAJB1	ENSP00000360124	ENSP00000254322	phosphoglucomutase 1	DnaJ (Hsp40) homolog, subfamily B, member 1; Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP	0.519
PGM1	DNAJB13	ENSP00000360124	ENSP00000344431	phosphoglucomutase 1	DnaJ (Hsp40) homolog, subfamily B, member 13; May be involved in inhibiting testis spermatogenesis apoptosis	0.519

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