DGKD protein (Homo sapiens) - STRING network view

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DGKD

diacylglycerol kinase, delta 130kDa; May function as signaling molecule (1214 aa)

Predicted Functional Partners:

AGPAT4

0.906

PLD4

0.905

PLD3

0.905

LPL

0.904

AGPAT3

0.903

PLCB4

0.902

EPT1

0.901

PNLIP

0.900

PLCD1

0.900

CDS2

0.900

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGPAT3	CDS2	ENSP00000291572	ENSP00000419879	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.954
AGPAT3	DGKD	ENSP00000291572	ENSP00000264057	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	0.903
AGPAT3	PLD3	ENSP00000291572	ENSP00000348901	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	phospholipase D family, member 3	0.900
AGPAT3	PLD4	ENSP00000291572	ENSP00000376372	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	phospholipase D family, member 4	0.900
AGPAT4	CDS2	ENSP00000314036	ENSP00000419879	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.957
AGPAT4	DGKD	ENSP00000314036	ENSP00000264057	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	0.906
AGPAT4	PLD3	ENSP00000314036	ENSP00000348901	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	phospholipase D family, member 3	0.900
AGPAT4	PLD4	ENSP00000314036	ENSP00000376372	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	phospholipase D family, member 4	0.900
CDS2	AGPAT3	ENSP00000419879	ENSP00000291572	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	0.954
CDS2	AGPAT4	ENSP00000419879	ENSP00000314036	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	0.957
CDS2	DGKD	ENSP00000419879	ENSP00000264057	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	0.900
CDS2	PLD3	ENSP00000419879	ENSP00000348901	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	phospholipase D family, member 3	0.900
CDS2	PLD4	ENSP00000419879	ENSP00000376372	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	phospholipase D family, member 4	0.900
DGKD	AGPAT3	ENSP00000264057	ENSP00000291572	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	1-acylglycerol-3-phosphate O-acyltransferase 3; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16-0-C20-4 at the sn-1 position using C18-1, C20-4 or C18-2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18-1 or C20-4-CoA	0.903
DGKD	AGPAT4	ENSP00000264057	ENSP00000314036	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity)	0.906
DGKD	CDS2	ENSP00000264057	ENSP00000419879	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2	0.900
DGKD	EPT1	ENSP00000264057	ENSP00000260585	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific); Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via ’Kennedy’ pathway	0.901
DGKD	LPL	ENSP00000264057	ENSP00000309757	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	lipoprotein lipase; The primary function of this lipase is the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins (VLDL). Binding to heparin sulfate proteogylcans at the cell surface is vital to the function. The apolipoprotein, APOC2, acts as a coactivator of LPL activity in the presence of lipids on the luminal surface of vascular endothelium (By similarity)	0.904
DGKD	PLCB4	ENSP00000264057	ENSP00000334105	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	phospholipase C, beta 4	0.902
DGKD	PLCD1	ENSP00000264057	ENSP00000430344	diacylglycerol kinase, delta 130kDa; May function as signaling molecule	phospholipase C, delta 1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Essential for trophoblast and placental development	0.900

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