| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COPZ1 | COPZ2 | ENSP00000262061 | ENSP00000006101 | coatomer protein complex, subunit zeta 1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; th [...] | coatomer protein complex, subunit zeta 2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-diss [...] | 0.900 |
| COPZ1 | R3HDM1 | ENSP00000262061 | ENSP00000264160 | coatomer protein complex, subunit zeta 1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; th [...] | R3H domain containing 1 | 0.461 |
| COPZ2 | COPZ1 | ENSP00000006101 | ENSP00000262061 | coatomer protein complex, subunit zeta 2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-diss [...] | coatomer protein complex, subunit zeta 1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; th [...] | 0.900 |
| COPZ2 | R3HDM1 | ENSP00000006101 | ENSP00000264160 | coatomer protein complex, subunit zeta 2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-diss [...] | R3H domain containing 1 | 0.706 |
| MAP3K19 | R3HDM1 | ENSP00000365005 | ENSP00000264160 | mitogen-activated protein kinase kinase kinase 19 | R3H domain containing 1 | 0.549 |
| MAP3K19 | UBXN4 | ENSP00000365005 | ENSP00000272638 | mitogen-activated protein kinase kinase kinase 19 | UBX domain protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD) | 0.653 |
| MAP3K19 | ZRANB3 | ENSP00000365005 | ENSP00000264159 | mitogen-activated protein kinase kinase kinase 19 | zinc finger, RAN-binding domain containing 3 | 0.647 |
| MATN2 | R3HDM1 | ENSP00000430487 | ENSP00000264160 | matrilin 2 | R3H domain containing 1 | 0.529 |
| MATN2 | ZRANB3 | ENSP00000430487 | ENSP00000264159 | matrilin 2 | zinc finger, RAN-binding domain containing 3 | 0.502 |
| MIB1 | R3HDM1 | ENSP00000261537 | ENSP00000264160 | mindbomb E3 ubiquitin protein ligase 1 | R3H domain containing 1 | 0.562 |
| PMPCB | R3HDM1 | ENSP00000249269 | ENSP00000264160 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | R3H domain containing 1 | 0.487 |
| PMPCB | UQCRC2 | ENSP00000249269 | ENSP00000268379 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | ubiquinol-cytochrome c reductase core protein II; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex | 0.975 |
| R3HDM1 | COPZ1 | ENSP00000264160 | ENSP00000262061 | R3H domain containing 1 | coatomer protein complex, subunit zeta 1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; th [...] | 0.461 |
| R3HDM1 | COPZ2 | ENSP00000264160 | ENSP00000006101 | R3H domain containing 1 | coatomer protein complex, subunit zeta 2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-diss [...] | 0.706 |
| R3HDM1 | MAP3K19 | ENSP00000264160 | ENSP00000365005 | R3H domain containing 1 | mitogen-activated protein kinase kinase kinase 19 | 0.549 |
| R3HDM1 | MATN2 | ENSP00000264160 | ENSP00000430487 | R3H domain containing 1 | matrilin 2 | 0.529 |
| R3HDM1 | MIB1 | ENSP00000264160 | ENSP00000261537 | R3H domain containing 1 | mindbomb E3 ubiquitin protein ligase 1 | 0.562 |
| R3HDM1 | PMPCB | ENSP00000264160 | ENSP00000249269 | R3H domain containing 1 | peptidase (mitochondrial processing) beta; Cleaves presequences (transit peptides) from mitochondrial protein precursors (By similarity) | 0.487 |
| R3HDM1 | UBXN4 | ENSP00000264160 | ENSP00000272638 | R3H domain containing 1 | UBX domain protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD) | 0.500 |
| R3HDM1 | UQCRC1 | ENSP00000264160 | ENSP00000203407 | R3H domain containing 1 | ubiquinol-cytochrome c reductase core protein I; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1 | 0.487 |
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