Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C18orf12 | ZNF638 | ENSP00000471539 | ENSP00000264447 | Protein HEIL1 | zinc finger protein 638 | 0.568 |
EFEMP2 | ZNF638 | ENSP00000309953 | ENSP00000264447 | EGF containing fibulin-like extracellular matrix protein 2 | zinc finger protein 638 | 0.624 |
FHL2 | UBC | ENSP00000322909 | ENSP00000344818 | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | ubiquitin C | 0.800 |
FHL2 | ZNF638 | ENSP00000322909 | ENSP00000264447 | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | zinc finger protein 638 | 0.934 |
GTF2E2 | UBC | ENSP00000348168 | ENSP00000344818 | general transcription factor IIE, polypeptide 2, beta 34kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | ubiquitin C | 0.620 |
GTF2E2 | YTHDC1 | ENSP00000348168 | ENSP00000339245 | general transcription factor IIE, polypeptide 2, beta 34kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | YTH domain containing 1; May be part of a signal transduction pathway that influences splice site selection (By similarity) | 0.503 |
GTF2E2 | ZNF638 | ENSP00000348168 | ENSP00000264447 | general transcription factor IIE, polypeptide 2, beta 34kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | zinc finger protein 638 | 0.601 |
PLSCR1 | UBC | ENSP00000345494 | ENSP00000344818 | phospholipid scramblase 1; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system | ubiquitin C | 0.854 |
PLSCR1 | ZNF638 | ENSP00000345494 | ENSP00000264447 | phospholipid scramblase 1; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system | zinc finger protein 638 | 0.554 |
PURA | UBC | ENSP00000332706 | ENSP00000344818 | purine-rich element binding protein A; This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination | ubiquitin C | 0.801 |
PURA | ZNF638 | ENSP00000332706 | ENSP00000264447 | purine-rich element binding protein A; This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination | zinc finger protein 638 | 0.773 |
UBC | FHL2 | ENSP00000344818 | ENSP00000322909 | ubiquitin C | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | 0.800 |
UBC | GTF2E2 | ENSP00000344818 | ENSP00000348168 | ubiquitin C | general transcription factor IIE, polypeptide 2, beta 34kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | 0.620 |
UBC | PLSCR1 | ENSP00000344818 | ENSP00000345494 | ubiquitin C | phospholipid scramblase 1; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system | 0.854 |
UBC | PURA | ENSP00000344818 | ENSP00000332706 | ubiquitin C | purine-rich element binding protein A; This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination | 0.801 |
UBC | YTHDC1 | ENSP00000344818 | ENSP00000339245 | ubiquitin C | YTH domain containing 1; May be part of a signal transduction pathway that influences splice site selection (By similarity) | 0.629 |
UBC | YY1 | ENSP00000344818 | ENSP00000262238 | ubiquitin C | YY1 transcription factor; Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5’-CCGCCATNTT-3’; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repre [...] | 0.991 |
UBC | ZNF638 | ENSP00000344818 | ENSP00000264447 | ubiquitin C | zinc finger protein 638 | 0.620 |
WASL | ZNF638 | ENSP00000223023 | ENSP00000264447 | Wiskott-Aldrich syndrome-like; Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression | zinc finger protein 638 | 0.644 |
YTHDC1 | GTF2E2 | ENSP00000339245 | ENSP00000348168 | YTH domain containing 1; May be part of a signal transduction pathway that influences splice site selection (By similarity) | general transcription factor IIE, polypeptide 2, beta 34kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | 0.503 |
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