SLC30A9 protein (Homo sapiens) - STRING network view

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SLC30A9

solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity) (568 aa)

Predicted Functional Partners:

SLC30A5

0.804

SLC30A7

0.789

SLC30A2

0.765

SLC30A6

0.751

SLC30A4

0.724

SLC30A3

0.722

PFKFB3

0.706

ATIC

0.705

SLC30A8

0.696

SLC30A1

0.694

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATIC	PFKFB3	ENSP00000236959	ENSP00000369100	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; Synthesis and degradation of fructose 2,6-bisphosphate	0.479
ATIC	SLC30A9	ENSP00000236959	ENSP00000264451	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.705
PFKFB3	ATIC	ENSP00000369100	ENSP00000236959	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; Synthesis and degradation of fructose 2,6-bisphosphate	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis	0.479
PFKFB3	SLC30A9	ENSP00000369100	ENSP00000264451	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; Synthesis and degradation of fructose 2,6-bisphosphate	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.706
SLC30A1	SLC30A6	ENSP00000355968	ENSP00000368648	solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	0.923
SLC30A1	SLC30A9	ENSP00000355968	ENSP00000264451	solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.694
SLC30A2	SLC30A7	ENSP00000363394	ENSP00000350278	solute carrier family 30 (zinc transporter), member 2	solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)	0.463
SLC30A2	SLC30A9	ENSP00000363394	ENSP00000264451	solute carrier family 30 (zinc transporter), member 2	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.765
SLC30A3	SLC30A7	ENSP00000233535	ENSP00000350278	solute carrier family 30 (zinc transporter), member 3; Involved in accumulation of zinc in synaptic vesicles (By similarity)	solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)	0.462
SLC30A3	SLC30A9	ENSP00000233535	ENSP00000264451	solute carrier family 30 (zinc transporter), member 3; Involved in accumulation of zinc in synaptic vesicles (By similarity)	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.722
SLC30A4	SLC30A6	ENSP00000261867	ENSP00000368648	solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	0.933
SLC30A4	SLC30A7	ENSP00000261867	ENSP00000350278	solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment	solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity)	0.454
SLC30A4	SLC30A9	ENSP00000261867	ENSP00000264451	solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.724
SLC30A5	SLC30A6	ENSP00000379836	ENSP00000368648	solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	0.720
SLC30A5	SLC30A9	ENSP00000379836	ENSP00000264451	solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.804
SLC30A6	SLC30A1	ENSP00000368648	ENSP00000355968	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell	0.923
SLC30A6	SLC30A4	ENSP00000368648	ENSP00000261867	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment	0.933
SLC30A6	SLC30A5	ENSP00000368648	ENSP00000379836	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP	0.720
SLC30A6	SLC30A8	ENSP00000368648	ENSP00000415011	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta- cells	0.826
SLC30A6	SLC30A9	ENSP00000368648	ENSP00000264451	solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity)	solute carrier family 30 (zinc transporter), member 9; Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity)	0.751

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