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STRINGSTRING
MYO18A MYO18A TADA3 TADA3 KLC1 KLC1 MYH8 MYH8 KIF3C KIF3C KIF3B KIF3B KIF26A KIF26A KIF3A KIF3A KIFAP3 KIFAP3 MYO5C MYO5C ENSG00000256500 ENSG00000256500
"KIF3C" - kinesin family member 3C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
KIF3Ckinesin family member 3C; Microtubule-based anterograde translocator for membranous organelles (By similarity) (793 aa)    
Predicted Functional Partners:
KIFAP3
kinesin-associated protein 3; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Binds to the tail domain of the KIF3A/KIF3B heterodimer to form a heterotrimeric KIF3 complex and may regulate the membrane binding of this complex (By similarity) (792 aa)
        score_image score_image score_image   0.977
KIF3A
kinesin family member 3A; Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation (By similarity) (699 aa)
        score_image score_image score_image score_image 0.962
KIF26A
kinesin family member 26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity) (1882 aa)
          score_image score_image score_image 0.916
KIF3B
kinesin family member 3B; Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity) (747 aa)
          score_image score_image score_image 0.901
ENSG00000256500
Kinesin light chain 1 (732 aa)
        score_image   score_image   0.847
KLC1
kinesin light chain 1 (618 aa)
        score_image   score_image   0.821
TADA3
transcriptional adaptor 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (432 aa)
        score_image   score_image   0.776
MYO5C
myosin VC; May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues (1742 aa)
        score_image   score_image   0.750
MYO18A
myosin XVIIIA; May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). In concert with LURAP1 and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (2054 aa)
        score_image   score_image   0.749
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal; Muscle contraction (1937 aa)
        score_image   score_image   0.749
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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