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PPP2R5C PPP2R5C PPP2R2A PPP2R2A PPP2R2C PPP2R2C PPP2R5A PPP2R5A PPP2CB PPP2CB PPP2R4 PPP2R4 PPP2CA PPP2CA PPP2R1A PPP2R1A PPP2R3A PPP2R3A CDC6 CDC6 NKD1 NKD1
"PPP2R3A" - protein phosphatase 2, regulatory subunit B'', alpha in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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PPP2R3Aprotein phosphatase 2, regulatory subunit B’’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment (1150 aa)    
Predicted Functional Partners:
PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis (589 aa)
        score_image score_image score_image   0.995
PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at ’Ser-259’ (309 aa)
        score_image score_image score_image   0.993
PPP2R5A
protein phosphatase 2, regulatory subunit B’, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment (486 aa)
          score_image score_image   0.976
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment (457 aa)
          score_image score_image   0.975
PPP2R5C
protein phosphatase 2, regulatory subunit B’, gamma; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage- induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation (555 aa)
          score_image score_image   0.973
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment (447 aa)
          score_image score_image   0.962
NKD1
naked cuticle homolog 1 (Drosophila); Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity (470 aa)
        score_image   score_image   0.959
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4 (323 aa)
        score_image score_image score_image   0.959
CDC6
cell division cycle 6 homolog (S. cerevisiae); Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated (560 aa)
      score_image score_image   score_image   0.950
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme; PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase (309 aa)
        score_image score_image score_image   0.948
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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