ACAD11 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACAD11

acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA (780 aa)

Predicted Functional Partners:

UGT3A1

0.740

UGT3A2

0.612

GHR

0.577

CCDC159

0.562

NUDT12

0.545

PEX5

0.485

KIAA0513

0.475

ACOXL

0.472

SCP2

0.458

TBKBP1

0.452

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAD11	ACOXL	ENSP00000264990	ENSP00000407761	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	acyl-CoA oxidase-like	0.472
ACAD11	CCDC159	ENSP00000264990	ENSP00000402239	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	coiled-coil domain containing 159	0.562
ACAD11	GHR	ENSP00000264990	ENSP00000230882	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	0.577
ACAD11	KIAA0513	ENSP00000264990	ENSP00000258180	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	KIAA0513	0.475
ACAD11	NUDT12	ENSP00000264990	ENSP00000230792	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	nudix (nucleoside diphosphate linked moiety X)-type motif 12; Hydrolyzes NAD(P)H to NMNH and AMP (2’,5’-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle	0.545
ACAD11	PEX5	ENSP00000264990	ENSP00000407401	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	0.485
ACAD11	SCP2	ENSP00000264990	ENSP00000360569	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	sterol carrier protein 2; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	0.458
ACAD11	TBKBP1	ENSP00000264990	ENSP00000354777	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	TBK1 binding protein 1; Adapter protein which constitutively binds TBK1 and IKBKE and may play a role in antiviral innate immunity (By similarity)	0.452
ACAD11	UGT3A1	ENSP00000264990	ENSP00000274278	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.740
ACAD11	UGT3A2	ENSP00000264990	ENSP00000282507	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	UDP glycosyltransferase 3 family, polypeptide A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.612
ACOXL	ACAD11	ENSP00000407761	ENSP00000264990	acyl-CoA oxidase-like	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.472
CCDC159	ACAD11	ENSP00000402239	ENSP00000264990	coiled-coil domain containing 159	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.562
GHR	ACAD11	ENSP00000230882	ENSP00000264990	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.577
GHR	UGT3A1	ENSP00000230882	ENSP00000274278	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.577
GHR	UGT3A2	ENSP00000230882	ENSP00000282507	growth hormone receptor; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity)	UDP glycosyltransferase 3 family, polypeptide A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)	0.562
KIAA0513	ACAD11	ENSP00000258180	ENSP00000264990	KIAA0513	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.475
NUDT12	ACAD11	ENSP00000230792	ENSP00000264990	nudix (nucleoside diphosphate linked moiety X)-type motif 12; Hydrolyzes NAD(P)H to NMNH and AMP (2’,5’-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.545
PEX5	ACAD11	ENSP00000407401	ENSP00000264990	peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.485
PEX5	SCP2	ENSP00000407401	ENSP00000360569	peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import	sterol carrier protein 2; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	0.992
SCP2	ACAD11	ENSP00000360569	ENSP00000264990	sterol carrier protein 2; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis	acyl-CoA dehydrogenase family, member 11; Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA	0.458

page 1 of 2

Experiments

Cooccurrence

Textmining

Neighborhood

Coexpression

Fusion

Databases

© STRING Consortium 2017

Credits

Access

Info

About