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C5orf51 C5orf51 UBE3C UBE3C FMR1 FMR1 RPL12 RPL12 FXR1 FXR1 TEX2 TEX2 CPEB4 CPEB4 FXR2 FXR2 PRSS12 PRSS12 TOB1 TOB1 NDST1 NDST1
"CPEB4" - cytoplasmic polyadenylation element binding protein 4 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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second shell of interactors
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Known Interactions
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from curated databases
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
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co-expression
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protein homology
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Score
CPEB4cytoplasmic polyadenylation element binding protein 4 (729 aa)    
Predicted Functional Partners:
FMR1
fragile X mental retardation 1; Translation repressor. Component of the CYFIP1-EIF4E- FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA- binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C) (632 aa)
            score_image   0.747
FXR1
fragile X mental retardation, autosomal homolog 1; RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulate intracellular transport and local translation of certain mRNAs (By similarity) (621 aa)
            score_image   0.747
FXR2
fragile X mental retardation, autosomal homolog 2; RNA-binding protein (673 aa)
            score_image   0.747
PRSS12
protease, serine, 12 (neurotrypsin, motopsin); Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations (By similarity) (875 aa)
            score_image   0.737
TEX2
testis expressed 2 (1134 aa)
            score_image   0.700
UBE3C
ubiquitin protein ligase E3C; E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either ’Lys-29’- or ’Lys-48’-linked polyubiquitin chains. Has preference for ’Lys-48’ linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo (1083 aa)
        score_image       0.644
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that [...] (882 aa)
        score_image       0.644
TOB1
transducer of ERBB2, 1; Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (345 aa)
        score_image   score_image   0.605
C5orf51
chromosome 5 open reading frame 51 (294 aa)
            score_image   0.499
RPL12
ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity) (165 aa)
            score_image   0.485
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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