node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C5orf46 | JAKMIP2 | ENSP00000315370 | ENSP00000265272 | chromosome 5 open reading frame 46 | janus kinase and microtubule interacting protein 2 | 0.511 |
CLASP1 | JAKMIP2 | ENSP00000263710 | ENSP00000265272 | cytoplasmic linker associated protein 1; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is re [...] | janus kinase and microtubule interacting protein 2 | 0.586 |
CLIP4 | JAKMIP2 | ENSP00000327009 | ENSP00000265272 | CAP-GLY domain containing linker protein family, member 4 | janus kinase and microtubule interacting protein 2 | 0.469 |
GABBR2 | JAKMIP2 | ENSP00000259455 | ENSP00000265272 | gamma-aminobutyric acid (GABA) B receptor, 2; Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high- voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a promi [...] | janus kinase and microtubule interacting protein 2 | 0.418 |
JAKMIP2 | C5orf46 | ENSP00000265272 | ENSP00000315370 | janus kinase and microtubule interacting protein 2 | chromosome 5 open reading frame 46 | 0.511 |
JAKMIP2 | CLASP1 | ENSP00000265272 | ENSP00000263710 | janus kinase and microtubule interacting protein 2 | cytoplasmic linker associated protein 1; Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is re [...] | 0.586 |
JAKMIP2 | CLIP4 | ENSP00000265272 | ENSP00000327009 | janus kinase and microtubule interacting protein 2 | CAP-GLY domain containing linker protein family, member 4 | 0.469 |
JAKMIP2 | GABBR2 | ENSP00000265272 | ENSP00000259455 | janus kinase and microtubule interacting protein 2 | gamma-aminobutyric acid (GABA) B receptor, 2; Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high- voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a promi [...] | 0.418 |
JAKMIP2 | PTK2 | ENSP00000265272 | ENSP00000341189 | janus kinase and microtubule interacting protein 2 | PTK2 protein tyrosine kinase 2; Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; req [...] | 0.440 |
JAKMIP2 | TRIM29 | ENSP00000265272 | ENSP00000343129 | janus kinase and microtubule interacting protein 2 | tripartite motif containing 29; It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line | 0.423 |
JAKMIP2 | TYK2 | ENSP00000265272 | ENSP00000264818 | janus kinase and microtubule interacting protein 2 | tyrosine kinase 2; Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain | 0.440 |
PTK2 | JAKMIP2 | ENSP00000341189 | ENSP00000265272 | PTK2 protein tyrosine kinase 2; Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; req [...] | janus kinase and microtubule interacting protein 2 | 0.440 |
TRIM29 | JAKMIP2 | ENSP00000343129 | ENSP00000265272 | tripartite motif containing 29; It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line | janus kinase and microtubule interacting protein 2 | 0.423 |
TYK2 | JAKMIP2 | ENSP00000264818 | ENSP00000265272 | tyrosine kinase 2; Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain | janus kinase and microtubule interacting protein 2 | 0.440 |