node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IMP3 | MRPS18A | ENSP00000326981 | ENSP00000361206 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | mitochondrial ribosomal protein S18A | 0.945 |
IMP3 | MRPS18C | ENSP00000326981 | ENSP00000295491 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | mitochondrial ribosomal protein S18C | 0.945 |
IMP3 | MRPS6 | ENSP00000326981 | ENSP00000382250 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | mitochondrial ribosomal protein S6 | 0.938 |
IMP3 | NHP2 | ENSP00000326981 | ENSP00000274606 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...] | 0.944 |
IMP3 | NHP2L1 | ENSP00000326981 | ENSP00000215956 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae); Binds to the 5’-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding | 0.879 |
IMP3 | RPP38 | ENSP00000326981 | ENSP00000367439 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | ribonuclease P/MRP 38kDa subunit; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5’-ends. RPP38 may associate transiently with RNase P RNA as a factor involved in the transport of H1 RNA to the putative site of its assembly in the cell, the nucleolus | 0.876 |
IMP3 | SSBP1 | ENSP00000326981 | ENSP00000265304 | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | single-stranded DNA binding protein 1, mitochondrial; This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA | 0.693 |
MRPS18A | IMP3 | ENSP00000361206 | ENSP00000326981 | mitochondrial ribosomal protein S18A | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | 0.945 |
MRPS18A | MRPS18C | ENSP00000361206 | ENSP00000295491 | mitochondrial ribosomal protein S18A | mitochondrial ribosomal protein S18C | 0.977 |
MRPS18A | MRPS6 | ENSP00000361206 | ENSP00000382250 | mitochondrial ribosomal protein S18A | mitochondrial ribosomal protein S6 | 0.986 |
MRPS18A | RPS9 | ENSP00000361206 | ENSP00000302896 | mitochondrial ribosomal protein S18A | ribosomal protein S9 | 0.945 |
MRPS18A | SSBP1 | ENSP00000361206 | ENSP00000265304 | mitochondrial ribosomal protein S18A | single-stranded DNA binding protein 1, mitochondrial; This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA | 0.844 |
MRPS18C | IMP3 | ENSP00000295491 | ENSP00000326981 | mitochondrial ribosomal protein S18C | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing | 0.945 |
MRPS18C | MRPS18A | ENSP00000295491 | ENSP00000361206 | mitochondrial ribosomal protein S18C | mitochondrial ribosomal protein S18A | 0.977 |
MRPS18C | MRPS33 | ENSP00000295491 | ENSP00000320567 | mitochondrial ribosomal protein S18C | mitochondrial ribosomal protein S33 | 0.493 |
MRPS18C | MRPS6 | ENSP00000295491 | ENSP00000382250 | mitochondrial ribosomal protein S18C | mitochondrial ribosomal protein S6 | 0.986 |
MRPS18C | RPS9 | ENSP00000295491 | ENSP00000302896 | mitochondrial ribosomal protein S18C | ribosomal protein S9 | 0.945 |
MRPS18C | SSBP1 | ENSP00000295491 | ENSP00000265304 | mitochondrial ribosomal protein S18C | single-stranded DNA binding protein 1, mitochondrial; This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA | 0.844 |
MRPS33 | MRPS18C | ENSP00000320567 | ENSP00000295491 | mitochondrial ribosomal protein S33 | mitochondrial ribosomal protein S18C | 0.493 |
MRPS33 | NDUFB2 | ENSP00000320567 | ENSP00000247866 | mitochondrial ribosomal protein S33 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone | 0.819 |