node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSP00000344789 | ENSP00000341044 | acetyl-CoA carboxylase alpha | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.999 |
ACACA | ACOX2 | ENSP00000344789 | ENSP00000307697 | acetyl-CoA carboxylase alpha | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | 0.661 |
ACACA | HSD17B11 | ENSP00000344789 | ENSP00000351035 | acetyl-CoA carboxylase alpha | hydroxysteroid (17-beta) dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma | 0.581 |
ACACA | PECR | ENSP00000344789 | ENSP00000265322 | acetyl-CoA carboxylase alpha | peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity | 0.607 |
ACACA | TECR | ENSP00000344789 | ENSP00000215567 | acetyl-CoA carboxylase alpha | trans-2,3-enoyl-CoA reductase; Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids | 0.520 |
ACACB | ACACA | ENSP00000341044 | ENSP00000344789 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acetyl-CoA carboxylase alpha | 0.999 |
ACACB | ACOX2 | ENSP00000341044 | ENSP00000307697 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | 0.672 |
ACACB | HSD17B11 | ENSP00000341044 | ENSP00000351035 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | hydroxysteroid (17-beta) dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma | 0.581 |
ACACB | PECR | ENSP00000341044 | ENSP00000265322 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity | 0.581 |
ACACB | TECR | ENSP00000341044 | ENSP00000215567 | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | trans-2,3-enoyl-CoA reductase; Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids | 0.517 |
ACOX2 | ACACA | ENSP00000307697 | ENSP00000344789 | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | acetyl-CoA carboxylase alpha | 0.661 |
ACOX2 | ACACB | ENSP00000307697 | ENSP00000341044 | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.672 |
ACOX2 | AMACR | ENSP00000307697 | ENSP00000371517 | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | alpha-methylacyl-CoA racemase | 0.976 |
ACOX2 | PECR | ENSP00000307697 | ENSP00000265322 | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity | 0.589 |
ACOX2 | PEX5 | ENSP00000307697 | ENSP00000407401 | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import | 0.819 |
AMACR | ACOX2 | ENSP00000371517 | ENSP00000307697 | alpha-methylacyl-CoA racemase | acyl-CoA oxidase 2, branched chain; Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids | 0.976 |
AMACR | PECR | ENSP00000371517 | ENSP00000265322 | alpha-methylacyl-CoA racemase | peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity | 0.567 |
AMACR | PEX5 | ENSP00000371517 | ENSP00000407401 | alpha-methylacyl-CoA racemase | peroxisomal biogenesis factor 5; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import | 0.479 |
HSD17B11 | ACACA | ENSP00000351035 | ENSP00000344789 | hydroxysteroid (17-beta) dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma | acetyl-CoA carboxylase alpha | 0.581 |
HSD17B11 | ACACB | ENSP00000351035 | ENSP00000341044 | hydroxysteroid (17-beta) dehydrogenase 11; Can convert androstan-3-alpha,17-beta-diol (3-alpha- diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor- associated antigen in cutaneous T-cell lymphoma | acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase | 0.581 |