APBA1 protein (Homo sapiens) - STRING network view

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APBA1

amyloid beta (A4) precursor protein-binding, family A, member 1 (837 aa)

Predicted Functional Partners:

CASK

0.964

APP

0.933

APLP2

0.875

STXBP1

0.862

C16orf70

0.798

MPP1

0.714

CASKIN1

0.709

APBB2

0.689

KIF17

0.683

FAM189A2

0.680

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	APBB2	ENSP00000265381	ENSP00000427211	amyloid beta (A4) precursor protein-binding, family A, member 1	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	0.689
APBA1	APLP2	ENSP00000265381	ENSP00000263574	amyloid beta (A4) precursor protein-binding, family A, member 1	amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)	0.875
APBA1	APP	ENSP00000265381	ENSP00000284981	amyloid beta (A4) precursor protein-binding, family A, member 1	amyloid beta (A4) precursor protein	0.933
APBA1	C16orf70	ENSP00000265381	ENSP00000219139	amyloid beta (A4) precursor protein-binding, family A, member 1	chromosome 16 open reading frame 70	0.798
APBA1	CASK	ENSP00000265381	ENSP00000367408	amyloid beta (A4) precursor protein-binding, family A, member 1	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.964
APBA1	CASKIN1	ENSP00000265381	ENSP00000345436	amyloid beta (A4) precursor protein-binding, family A, member 1	CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity)	0.709
APBA1	FAM189A2	ENSP00000265381	ENSP00000257515	amyloid beta (A4) precursor protein-binding, family A, member 1	family with sequence similarity 189, member A2	0.680
APBA1	KIF17	ENSP00000265381	ENSP00000247986	amyloid beta (A4) precursor protein-binding, family A, member 1	kinesin family member 17; Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules (By similarity)	0.683
APBA1	MPP1	ENSP00000265381	ENSP00000358547	amyloid beta (A4) precursor protein-binding, family A, member 1	membrane protein, palmitoylated 1, 55kDa; Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity)	0.714
APBA1	STXBP1	ENSP00000265381	ENSP00000362399	amyloid beta (A4) precursor protein-binding, family A, member 1	syntaxin binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1-1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions	0.862
APBB2	APBA1	ENSP00000427211	ENSP00000265381	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	amyloid beta (A4) precursor protein-binding, family A, member 1	0.689
APBB2	APLP2	ENSP00000427211	ENSP00000263574	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)	0.893
APBB2	APP	ENSP00000427211	ENSP00000284981	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	amyloid beta (A4) precursor protein	0.941
APBB2	KIF17	ENSP00000427211	ENSP00000247986	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	kinesin family member 17; Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules (By similarity)	0.407
APBB2	STXBP1	ENSP00000427211	ENSP00000362399	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	syntaxin binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1-1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions	0.493
APLP2	APBA1	ENSP00000263574	ENSP00000265381	amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)	amyloid beta (A4) precursor protein-binding, family A, member 1	0.875
APLP2	APBB2	ENSP00000263574	ENSP00000427211	amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	0.893
APLP2	APP	ENSP00000263574	ENSP00000284981	amyloid beta (A4) precursor-like protein 2; May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5’-GTCACATG-3’(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity)	amyloid beta (A4) precursor protein	0.595
APP	APBA1	ENSP00000284981	ENSP00000265381	amyloid beta (A4) precursor protein	amyloid beta (A4) precursor protein-binding, family A, member 1	0.933
APP	APBB2	ENSP00000284981	ENSP00000427211	amyloid beta (A4) precursor protein	amyloid beta (A4) precursor protein-binding, family B, member 2; May modulate the internalization of beta-amyloid precursor protein	0.941

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