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STRINGSTRING
ENSG00000257767 ENSG00000257767 AOX1 AOX1 ABAT ABAT ALDH6A1 ALDH6A1 HIBADH HIBADH ALDH7A1 ALDH7A1 ALDH1B1 ALDH1B1 UBC UBC ALDH9A1 ALDH9A1 ALDH3A2 ALDH3A2 HIBCH HIBCH
"HIBADH" - 3-hydroxyisobutyrate dehydrogenase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
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cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
HIBADH3-hydroxyisobutyrate dehydrogenase (336 aa)    
Predicted Functional Partners:
ALDH6A1
aldehyde dehydrogenase 6 family, member A1; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (535 aa)
    score_image score_image   score_image score_image   0.987
HIBCH
3-hydroxyisobutyryl-CoA hydrolase; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (386 aa)
  score_image   score_image   score_image score_image   0.986
ALDH1B1
aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (517 aa)
score_image     score_image   score_image score_image   0.941
ALDH9A1
aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
score_image     score_image   score_image score_image   0.923
ENSG00000257767
Uncharacterized protein (245 aa)
score_image     score_image   score_image score_image   0.923
ALDH3A2
aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (508 aa)
score_image         score_image score_image   0.922
ALDH7A1
aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
score_image     score_image   score_image score_image   0.921
ABAT
4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)
          score_image score_image   0.907
AOX1
aldehyde oxidase 1 (1338 aa)
          score_image score_image   0.907
UBC
ubiquitin C (685 aa)
        score_image       0.774
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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