LAMP3 protein (Homo sapiens) - STRING network view

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LAMP3

lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity (416 aa)

Predicted Functional Partners:

CD83

0.769

ABCA3

0.701

CD207

0.674

CD209

0.647

RAB9A

0.624

ITGB1

0.598

FLOT2

0.593

SRC

0.583

CCR7

0.581

ITGAX

0.574

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA3	LAMP3	ENSP00000301732	ENSP00000265598	ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.701
CCR7	CD207	ENSP00000246657	ENSP00000386378	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	0.662
CCR7	CD209	ENSP00000246657	ENSP00000315477	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	CD209 molecule	0.645
CCR7	CD83	ENSP00000246657	ENSP00000368450	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.844
CCR7	ITGAX	ENSP00000246657	ENSP00000268296	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis	0.826
CCR7	LAMP3	ENSP00000246657	ENSP00000265598	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.581
CD207	CCR7	ENSP00000386378	ENSP00000246657	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	0.662
CD207	CD83	ENSP00000386378	ENSP00000368450	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.723
CD207	ITGAX	ENSP00000386378	ENSP00000268296	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis	0.799
CD207	LAMP3	ENSP00000386378	ENSP00000265598	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.674
CD209	CCR7	ENSP00000315477	ENSP00000246657	CD209 molecule	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	0.645
CD209	CD83	ENSP00000315477	ENSP00000368450	CD209 molecule	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.839
CD209	ITGAX	ENSP00000315477	ENSP00000268296	CD209 molecule	integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis	0.764
CD209	LAMP3	ENSP00000315477	ENSP00000265598	CD209 molecule	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.647
CD209	SRC	ENSP00000315477	ENSP00000350941	CD209 molecule	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian); Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to f [...]	0.910
CD83	CCR7	ENSP00000368450	ENSP00000246657	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	chemokine (C-C motif) receptor 7; Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions	0.844
CD83	CD207	ENSP00000368450	ENSP00000386378	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	CD207 molecule, langerin; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. [...]	0.723
CD83	CD209	ENSP00000368450	ENSP00000315477	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	CD209 molecule	0.839
CD83	ITGAX	ENSP00000368450	ENSP00000268296	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	integrin, alpha X (complement component 3 receptor 4 subunit); Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis	0.849
CD83	LAMP3	ENSP00000368450	ENSP00000265598	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	lysosomal-associated membrane protein 3; May play a role in dendritic cell function and in adaptive immunity	0.769

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