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STRINGSTRING
SLC4A4 SLC4A4 CA2 CA2 SLC4A8 SLC4A8 MUC5AC MUC5AC FOXI1 FOXI1 SLC26A4 SLC26A4 SCNN1A SCNN1A GJB2 GJB2 NKX2-1 NKX2-1 MYO15A MYO15A NOS1 NOS1
"SLC26A4" - solute carrier family 26, member 4 in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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SLC26A4solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide (780 aa)    
Predicted Functional Partners:
FOXI1
forkhead box I1; Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity) (378 aa)
            score_image   0.981
CA2
carbonic anhydrase II; Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye (260 aa)
            score_image   0.897
NKX2-1
NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis (401 aa)
            score_image   0.889
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming (623 aa)
            score_image   0.831
GJB2
gap junction protein, beta 2, 26kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell (By similarity) (226 aa)
            score_image   0.813
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (728 aa)
            score_image   0.803
NOS1
nitric oxide synthase 1 (neuronal); Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (1468 aa)
      score_image     score_image   0.799
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8; Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+)-HCO3(-) stoichiometry of 2-1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity (1093 aa)
            score_image   0.772
MYO15A
myosin XVA; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Required for the arrangement of stereocilia in mature hair bundles (By similarity) (3530 aa)
            score_image   0.761
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4 (1094 aa)
            score_image   0.730
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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