node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD5 | FSCN3 | ENSP00000367631 | ENSP00000265825 | ankyrin repeat domain 5 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.617 |
ANKRD5 | TCFL5 | ENSP00000367631 | ENSP00000334294 | ankyrin repeat domain 5 | transcription factor-like 5 (basic helix-loop-helix); Putative transcription factor. Isoform 3 may play a role in early spermatogenesis | 0.466 |
ANKRD5 | ZPBP | ENSP00000367631 | ENSP00000046087 | ankyrin repeat domain 5 | zona pellucida binding protein; May be implicated in gamete interaction during fertilization | 0.529 |
ESPN | FSCN3 | ENSP00000367059 | ENSP00000265825 | espin; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity) | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.539 |
ESPN | TDO2 | ENSP00000367059 | ENSP00000444788 | espin; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity) | tryptophan 2,3-dioxygenase; Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity) | 0.591 |
ESPNL | FSCN3 | ENSP00000339115 | ENSP00000265825 | espin-like | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.616 |
ESPNL | TDO2 | ENSP00000339115 | ENSP00000444788 | espin-like | tryptophan 2,3-dioxygenase; Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity) | 0.591 |
FSCN3 | ANKRD5 | ENSP00000265825 | ENSP00000367631 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | ankyrin repeat domain 5 | 0.617 |
FSCN3 | ESPN | ENSP00000265825 | ENSP00000367059 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | espin; Multifunctional actin-bundling protein. Plays a major role in regulating the organization, dimensions, dynamics and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in variouS mechanosensory and chemosensory cells (By similarity) | 0.539 |
FSCN3 | ESPNL | ENSP00000265825 | ENSP00000339115 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | espin-like | 0.616 |
FSCN3 | GTSF1L | ENSP00000265825 | ENSP00000362094 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | gametocyte specific factor 1-like | 0.499 |
FSCN3 | PLA2G4E | ENSP00000265825 | ENSP00000382434 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | phospholipase A2, group IVE; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position (By similarity) | 0.660 |
FSCN3 | POLR3A | ENSP00000265825 | ENSP00000361446 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | polymerase (RNA) III (DNA directed) polypeptide A, 155kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is th [...] | 0.485 |
FSCN3 | TAF9B | ENSP00000265825 | ENSP00000339917 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription | 0.578 |
FSCN3 | TCFL5 | ENSP00000265825 | ENSP00000334294 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | transcription factor-like 5 (basic helix-loop-helix); Putative transcription factor. Isoform 3 may play a role in early spermatogenesis | 0.482 |
FSCN3 | TDO2 | ENSP00000265825 | ENSP00000444788 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | tryptophan 2,3-dioxygenase; Incorporates oxygen into the indole moiety of tryptophan. Has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin (By similarity) | 0.485 |
FSCN3 | ZPBP | ENSP00000265825 | ENSP00000046087 | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | zona pellucida binding protein; May be implicated in gamete interaction during fertilization | 0.504 |
GTSF1L | FSCN3 | ENSP00000362094 | ENSP00000265825 | gametocyte specific factor 1-like | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.499 |
PLA2G4E | FSCN3 | ENSP00000382434 | ENSP00000265825 | phospholipase A2, group IVE; Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position (By similarity) | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.660 |
POLR3A | FSCN3 | ENSP00000361446 | ENSP00000265825 | polymerase (RNA) III (DNA directed) polypeptide A, 155kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is th [...] | fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus); Acts as an actin bundling protein (By similarity) | 0.485 |