| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARFGAP1 | ARFRP1 | ENSP00000314615 | ENSP00000326884 | ADP-ribosylation factor GTPase activating protein 1 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | 0.641 |
| ARFGAP1 | ARL4A | ENSP00000314615 | ENSP00000349250 | ADP-ribosylation factor GTPase activating protein 1 | ADP-ribosylation factor-like 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form | 0.625 |
| ARFGAP1 | ELMO3 | ENSP00000314615 | ENSP00000377566 | ADP-ribosylation factor GTPase activating protein 1 | engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) | 0.450 |
| ARFGAP1 | ELMOD1 | ENSP00000314615 | ENSP00000265840 | ADP-ribosylation factor GTPase activating protein 1 | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.574 |
| ARFGAP1 | ELMOD3 | ENSP00000314615 | ENSP00000318264 | ADP-ribosylation factor GTPase activating protein 1 | ELMO/CED-12 domain containing 3 | 0.493 |
| ARFRP1 | ARFGAP1 | ENSP00000326884 | ENSP00000314615 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | ADP-ribosylation factor GTPase activating protein 1 | 0.641 |
| ARFRP1 | ELMOD1 | ENSP00000326884 | ENSP00000265840 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.604 |
| ARFRP1 | ELMOD3 | ENSP00000326884 | ENSP00000318264 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | ELMO/CED-12 domain containing 3 | 0.402 |
| ARL4A | ARFGAP1 | ENSP00000349250 | ENSP00000314615 | ADP-ribosylation factor-like 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form | ADP-ribosylation factor GTPase activating protein 1 | 0.625 |
| ARL4A | ELMO3 | ENSP00000349250 | ENSP00000377566 | ADP-ribosylation factor-like 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form | engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) | 0.568 |
| ARL4A | ELMOD1 | ENSP00000349250 | ENSP00000265840 | ADP-ribosylation factor-like 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.500 |
| ELMO1 | ELMO2 | ENSP00000312185 | ENSP00000290246 | engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 | engulfment and cell motility 2 | 0.900 |
| ELMO1 | ELMOD1 | ENSP00000312185 | ENSP00000265840 | engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.613 |
| ELMO1 | ELMOD3 | ENSP00000312185 | ENSP00000318264 | engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 | ELMO/CED-12 domain containing 3 | 0.606 |
| ELMO2 | ELMO1 | ENSP00000290246 | ENSP00000312185 | engulfment and cell motility 2 | engulfment and cell motility 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 | 0.900 |
| ELMO2 | ELMOD1 | ENSP00000290246 | ENSP00000265840 | engulfment and cell motility 2 | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.612 |
| ELMO2 | ELMOD3 | ENSP00000290246 | ENSP00000318264 | engulfment and cell motility 2 | ELMO/CED-12 domain containing 3 | 0.629 |
| ELMO3 | ARFGAP1 | ENSP00000377566 | ENSP00000314615 | engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) | ADP-ribosylation factor GTPase activating protein 1 | 0.450 |
| ELMO3 | ARL4A | ENSP00000377566 | ENSP00000349250 | engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) | ADP-ribosylation factor-like 4A; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form | 0.568 |
| ELMO3 | ELMOD1 | ENSP00000377566 | ENSP00000265840 | engulfment and cell motility 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) | ELMO/CED-12 domain containing 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family | 0.738 |
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