node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCNAB1 | KCNAB2 | ENSP00000419952 | ENSP00000367323 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | 0.902 |
KCNAB1 | KCNAB3 | ENSP00000419952 | ENSP00000302719 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 | 0.903 |
KCNAB1 | KCNC1 | ENSP00000419952 | ENSP00000265969 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, Shaw-related subfamily, member 1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient | 0.946 |
KCNAB1 | KCNC2 | ENSP00000419952 | ENSP00000449253 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, Shaw-related subfamily, member 2; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly (By similarity) | 0.933 |
KCNAB1 | KCNG3 | ENSP00000419952 | ENSP00000304127 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily G, member 3; Potassium channel subunit. Modulates channel activity | 0.940 |
KCNAB1 | KCNH1 | ENSP00000419952 | ENSP00000271751 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts | 0.924 |
KCNAB1 | KCNH2 | ENSP00000419952 | ENSP00000262186 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 | 0.942 |
KCNAB1 | KCNIP1 | ENSP00000419952 | ENSP00000395323 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | Kv channel interacting protein 1; Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Probably modulates channels density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Seems to be involved in KCND2 trafficking to the cell surface | 0.450 |
KCNAB1 | KCNIP2 | ENSP00000419952 | ENSP00000420040 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | Kv channel interacting protein 2 | 0.510 |
KCNAB1 | KCNV2 | ENSP00000419952 | ENSP00000371514 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | potassium channel, subfamily V, member 2; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values | 0.919 |
KCNAB2 | KCNAB1 | ENSP00000367323 | ENSP00000419952 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.902 |
KCNAB2 | KCNAB3 | ENSP00000367323 | ENSP00000302719 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 | 0.903 |
KCNAB2 | KCNC1 | ENSP00000367323 | ENSP00000265969 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, Shaw-related subfamily, member 1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient | 0.949 |
KCNAB2 | KCNC2 | ENSP00000367323 | ENSP00000449253 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, Shaw-related subfamily, member 2; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Channel properties are modulated by subunit assembly (By similarity) | 0.929 |
KCNAB2 | KCNG3 | ENSP00000367323 | ENSP00000304127 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, subfamily G, member 3; Potassium channel subunit. Modulates channel activity | 0.943 |
KCNAB2 | KCNH1 | ENSP00000367323 | ENSP00000271751 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, subfamily H (eag-related), member 1; Pore-forming (alpha) subunit of voltage-gated non- inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Mediates IK(NI) current in myoblasts | 0.929 |
KCNAB2 | KCNH2 | ENSP00000367323 | ENSP00000262186 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium voltage-gated channel, subfamily H (eag-related), member 2; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1 | 0.933 |
KCNAB2 | KCNIP2 | ENSP00000367323 | ENSP00000420040 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | Kv channel interacting protein 2 | 0.416 |
KCNAB2 | KCNV2 | ENSP00000367323 | ENSP00000371514 | potassium voltage-gated channel, shaker-related subfamily, beta member 2 | potassium channel, subfamily V, member 2; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values | 0.917 |
KCNAB3 | KCNAB1 | ENSP00000302719 | ENSP00000419952 | potassium voltage-gated channel, shaker-related subfamily, beta member 3; Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5 | potassium voltage-gated channel, shaker-related subfamily, beta member 1 | 0.903 |