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STRINGSTRING
CPEB3 CPEB3 TNKS1BP1 TNKS1BP1 C2orf29 C2orf29 CNOT1 CNOT1 CNOT10 CNOT10 CNOT7 CNOT7 CNOT6L CNOT6L CNOT6 CNOT6 CNOT8 CNOT8 RQCD1 RQCD1 TOB1 TOB1
"CPEB3" - cytoplasmic polyadenylation element binding protein 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small nodes:
protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
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co-expression
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protein homology
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CPEB3cytoplasmic polyadenylation element binding protein 3 (698 aa)    
Predicted Functional Partners:
CNOT7
CCR4-NOT transcription complex, subunit 7; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translation [...] (285 aa)
         score_image score_image score_image   0.964
TOB1
transducer of ERBB2, 1; Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex (345 aa)
         score_image score_image score_image   0.964
CNOT6L
CCR4-NOT transcription complex, subunit 6-like; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3 [...] (555 aa)
           score_image score_image   0.940
CNOT6
CCR4-NOT transcription complex, subunit 6; Poly(A) nuclease with 3’-5’ RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein- coding determinant of instability (mCRD) of the FOS gene in the cyto [...] (557 aa)
           score_image score_image   0.932
CNOT8
CCR4-NOT transcription complex, subunit 8; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be [...] (292 aa)
           score_image score_image   0.922
CNOT1
CCR4-NOT transcription complex, subunit 1 (2376 aa)
           score_image score_image   0.916
CNOT10
CCR4-NOT transcription complex, subunit 10 (744 aa)
           score_image score_image   0.910
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe); Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such a [...] (299 aa)
           score_image score_image   0.901
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa (1729 aa)
           score_image     0.900
C2orf29
chromosome 2 open reading frame 29; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function (510 aa)
           score_image     0.900
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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