| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EEF1G | RBM6 | ENSP00000331901 | ENSP00000266022 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | 0.557 |
| EEF1G | SUMO2 | ENSP00000331901 | ENSP00000405965 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | 0.586 |
| EEF1G | UBC | ENSP00000331901 | ENSP00000344818 | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | ubiquitin C | 0.998 |
| LYPLA2 | RBM6 | ENSP00000363638 | ENSP00000266022 | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | 0.536 |
| LYPLA2 | UBC | ENSP00000363638 | ENSP00000344818 | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | ubiquitin C | 0.721 |
| LYPLA2 | ZFAND6 | ENSP00000363638 | ENSP00000261749 | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | zinc finger, AN1-type domain 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of ’Lys-48’- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity) | 0.661 |
| RBM6 | EEF1G | ENSP00000266022 | ENSP00000331901 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.557 |
| RBM6 | LYPLA2 | ENSP00000266022 | ENSP00000363638 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | 0.536 |
| RBM6 | SUMO2 | ENSP00000266022 | ENSP00000405965 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | 0.507 |
| RBM6 | UBC | ENSP00000266022 | ENSP00000344818 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | ubiquitin C | 0.483 |
| RBM6 | ZFAND6 | ENSP00000266022 | ENSP00000261749 | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | zinc finger, AN1-type domain 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of ’Lys-48’- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity) | 0.527 |
| SUMO2 | EEF1G | ENSP00000405965 | ENSP00000331901 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.586 |
| SUMO2 | RBM6 | ENSP00000405965 | ENSP00000266022 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | 0.507 |
| SUMO2 | UBC | ENSP00000405965 | ENSP00000344818 | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | ubiquitin C | 0.999 |
| UBC | EEF1G | ENSP00000344818 | ENSP00000331901 | ubiquitin C | eukaryotic translation elongation factor 1 gamma; Probably plays a role in anchoring the complex to other cellular components | 0.998 |
| UBC | LYPLA2 | ENSP00000344818 | ENSP00000363638 | ubiquitin C | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | 0.721 |
| UBC | RBM6 | ENSP00000344818 | ENSP00000266022 | ubiquitin C | RNA binding motif protein 6; Specifically binds poly(G) RNA homopolymers in vitro | 0.483 |
| UBC | SUMO2 | ENSP00000344818 | ENSP00000405965 | ubiquitin C | SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduc [...] | 0.999 |
| UBC | ZFAND6 | ENSP00000344818 | ENSP00000261749 | ubiquitin C | zinc finger, AN1-type domain 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of ’Lys-48’- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity) | 0.882 |
| ZFAND6 | LYPLA2 | ENSP00000261749 | ENSP00000363638 | zinc finger, AN1-type domain 6; Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of ’Lys-48’- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity) | lysophospholipase II; May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity (By similarity). Deacylates GAP43 | 0.661 |
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