LLPH protein (Homo sapiens) - STRING network view

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LLPH

LLP homolog, long-term synaptic facilitation (Aplysia) (129 aa)

Predicted Functional Partners:

NHP2

0.733

POLR1D

0.707

NOP16

0.657

NUDT7

0.545

RNF219

0.503

KIAA1210

0.502

TMBIM4

0.450

TNS1

0.444

SMC2

0.444

ENSG00000228144

0.436

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000228144	LLPH	ENSP00000454670	ENSP00000266604	Protein lifeguard 4; Uncharacterized protein	LLP homolog, long-term synaptic facilitation (Aplysia)	0.436
KIAA1210	LLPH	ENSP00000384670	ENSP00000266604	KIAA1210	LLP homolog, long-term synaptic facilitation (Aplysia)	0.502
LLPH	ENSG00000228144	ENSP00000266604	ENSP00000454670	LLP homolog, long-term synaptic facilitation (Aplysia)	Protein lifeguard 4; Uncharacterized protein	0.436
LLPH	KIAA1210	ENSP00000266604	ENSP00000384670	LLP homolog, long-term synaptic facilitation (Aplysia)	KIAA1210	0.502
LLPH	NHP2	ENSP00000266604	ENSP00000274606	LLP homolog, long-term synaptic facilitation (Aplysia)	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	0.733
LLPH	NOP16	ENSP00000266604	ENSP00000373810	LLP homolog, long-term synaptic facilitation (Aplysia)	NOP16 nucleolar protein homolog (yeast)	0.657
LLPH	NUDT7	ENSP00000266604	ENSP00000268533	LLP homolog, long-term synaptic facilitation (Aplysia)	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	0.545
LLPH	POLR1D	ENSP00000266604	ENSP00000302478	LLP homolog, long-term synaptic facilitation (Aplysia)	polymerase (RNA) I polypeptide D, 16kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively	0.707
LLPH	RNF219	ENSP00000266604	ENSP00000282003	LLP homolog, long-term synaptic facilitation (Aplysia)	ring finger protein 219	0.503
LLPH	SMC2	ENSP00000266604	ENSP00000286398	LLP homolog, long-term synaptic facilitation (Aplysia)	structural maintenance of chromosomes 2; Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases	0.444
LLPH	TMBIM4	ENSP00000266604	ENSP00000350965	LLP homolog, long-term synaptic facilitation (Aplysia)	transmembrane BAX inhibitor motif containing 4; Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release	0.450
LLPH	TNS1	ENSP00000266604	ENSP00000171887	LLP homolog, long-term synaptic facilitation (Aplysia)	tensin 1; May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton	0.444
NHP2	LLPH	ENSP00000274606	ENSP00000266604	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	LLP homolog, long-term synaptic facilitation (Aplysia)	0.733
NHP2	NOP16	ENSP00000274606	ENSP00000373810	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	NOP16 nucleolar protein homolog (yeast)	0.899
NHP2	POLR1D	ENSP00000274606	ENSP00000302478	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	polymerase (RNA) I polypeptide D, 16kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively	0.912
NOP16	LLPH	ENSP00000373810	ENSP00000266604	NOP16 nucleolar protein homolog (yeast)	LLP homolog, long-term synaptic facilitation (Aplysia)	0.657
NOP16	NHP2	ENSP00000373810	ENSP00000274606	NOP16 nucleolar protein homolog (yeast)	NHP2 ribonucleoprotein homolog (yeast); Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcr [...]	0.899
NOP16	POLR1D	ENSP00000373810	ENSP00000302478	NOP16 nucleolar protein homolog (yeast)	polymerase (RNA) I polypeptide D, 16kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively	0.678
NUDT7	LLPH	ENSP00000268533	ENSP00000266604	nudix (nucleoside diphosphate linked moiety X)-type motif 7; Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3’,5’-ADP and the corresponding 4’-phosphopantetheine derivative as products. CoA into 3’,5’-ADP and 4’- phosphopantetheine. Has no activity toward NDP-sugars, CDP- alcohols, (deoxy)nucleoside 5’-triphosphates, nucleoside 5’-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5’-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, [...]	LLP homolog, long-term synaptic facilitation (Aplysia)	0.545
POLR1D	LLPH	ENSP00000302478	ENSP00000266604	polymerase (RNA) I polypeptide D, 16kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively	LLP homolog, long-term synaptic facilitation (Aplysia)	0.707

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