Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
TTC39C TTC39C AGMAT AGMAT AVPI1 AVPI1 ARG1 ARG1 UROC1 UROC1 HAL HAL AMDHD1 AMDHD1 ARG2 ARG2 FTCD FTCD CTRB2 CTRB2 TMEM144 TMEM144
"AMDHD1" - amidohydrolase domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMDHD1amidohydrolase domain containing 1 (426 aa)    
Predicted Functional Partners:
UROC1
urocanate hydratase 1 (736 aa)
score_image   score_image score_image   score_image score_image   0.988
FTCD
formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (541 aa)
score_image   score_image score_image   score_image score_image   0.985
HAL
histidine ammonia-lyase (657 aa)
score_image score_image score_image score_image     score_image   0.926
AGMAT
agmatine ureohydrolase (agmatinase) (352 aa)
score_image     score_image     score_image   0.511
TMEM144
transmembrane protein 144 (345 aa)
            score_image   0.507
ARG1
arginase, liver (322 aa)
score_image           score_image   0.484
ARG2
arginase, type II; May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders (354 aa)
score_image           score_image   0.484
CTRB2
chymotrypsinogen B2 (263 aa)
            score_image   0.472
AVPI1
arginine vasopressin-induced 1; May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling (By similarity) (147 aa)
            score_image   0.465
TTC39C
tetratricopeptide repeat domain 39C (583 aa)
            score_image   0.457
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (39%)