node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CIRH1A | HEATR1 | ENSP00000327179 | ENSP00000355541 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | 0.988 |
CIRH1A | MKI67IP | ENSP00000327179 | ENSP00000285814 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.784 |
CIRH1A | NOL10 | ENSP00000327179 | ENSP00000371101 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | nucleolar protein 10 | 0.974 |
CIRH1A | NOP56 | ENSP00000327179 | ENSP00000370589 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.936 |
CIRH1A | NOP58 | ENSP00000327179 | ENSP00000264279 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) | 0.943 |
CIRH1A | NOP9 | ENSP00000327179 | ENSP00000267425 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | NOP9 nucleolar protein homolog (yeast) | 0.960 |
CIRH1A | PDCD11 | ENSP00000327179 | ENSP00000358812 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA | 0.967 |
CIRH1A | RBM19 | ENSP00000327179 | ENSP00000261741 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.963 |
CIRH1A | RRP12 | ENSP00000327179 | ENSP00000360031 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.930 |
CIRH1A | TBL3 | ENSP00000327179 | ENSP00000454836 | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | transducin (beta)-like 3 | 0.985 |
HEATR1 | CIRH1A | ENSP00000355541 | ENSP00000327179 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | cirrhosis, autosomal recessive 1A (cirhin); May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV | 0.988 |
HEATR1 | MKI67IP | ENSP00000355541 | ENSP00000285814 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | MKI67 (FHA domain) interacting nucleolar phosphoprotein | 0.848 |
HEATR1 | NOL10 | ENSP00000355541 | ENSP00000371101 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | nucleolar protein 10 | 0.869 |
HEATR1 | NOP56 | ENSP00000355541 | ENSP00000370589 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | NOP56 ribonucleoprotein homolog (yeast); Involved in the early to middle stages of 60S ribosomal subunit biogenesis | 0.978 |
HEATR1 | NOP58 | ENSP00000355541 | ENSP00000264279 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | NOP58 ribonucleoprotein homolog (yeast); Required for 60S ribosomal subunit biogenesis (By similarity) | 0.980 |
HEATR1 | NOP9 | ENSP00000355541 | ENSP00000267425 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | NOP9 nucleolar protein homolog (yeast) | 0.895 |
HEATR1 | PDCD11 | ENSP00000355541 | ENSP00000358812 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | programmed cell death 11; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA | 0.994 |
HEATR1 | RBM19 | ENSP00000355541 | ENSP00000261741 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | RNA binding motif protein 19; Plays a role in embryo pre-implantation development (By similarity) | 0.920 |
HEATR1 | RRP12 | ENSP00000355541 | ENSP00000360031 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | ribosomal RNA processing 12 homolog (S. cerevisiae) | 0.995 |
HEATR1 | TBL3 | ENSP00000355541 | ENSP00000454836 | HEAT repeat containing 1; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity) | transducin (beta)-like 3 | 0.998 |