| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQP1 | AQP2 | ENSP00000311165 | ENSP00000199280 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.909 |
| AQP1 | DNAH8 | ENSP00000311165 | ENSP00000333363 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | 0.658 |
| AQP1 | RHCG | ENSP00000311165 | ENSP00000268122 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | Rh family, C glycoprotein; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion | 0.507 |
| AQP1 | SLC9A3 | ENSP00000311165 | ENSP00000264938 | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction | 0.753 |
| AQP2 | AQP1 | ENSP00000199280 | ENSP00000311165 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.909 |
| AQP2 | ATP6V0A4 | ENSP00000199280 | ENSP00000253856 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | 0.560 |
| AQP2 | DNAH8 | ENSP00000199280 | ENSP00000333363 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | 0.724 |
| AQP2 | RHCG | ENSP00000199280 | ENSP00000268122 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | Rh family, C glycoprotein; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion | 0.466 |
| AQP2 | SLC26A4 | ENSP00000199280 | ENSP00000265715 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.585 |
| AQP2 | SLC9A3 | ENSP00000199280 | ENSP00000264938 | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction | 0.793 |
| ATP6V0A4 | AQP2 | ENSP00000253856 | ENSP00000199280 | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.560 |
| ATP6V0A4 | DNAH8 | ENSP00000253856 | ENSP00000333363 | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | 0.738 |
| ATP6V0A4 | RHCG | ENSP00000253856 | ENSP00000268122 | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | Rh family, C glycoprotein; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion | 0.745 |
| ATP6V0A4 | SLC26A4 | ENSP00000253856 | ENSP00000265715 | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | solute carrier family 26, member 4; Sodium-independent transporter of chloride and iodide | 0.710 |
| ATP6V0A4 | SLC9A3 | ENSP00000253856 | ENSP00000264938 | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction | 0.621 |
| CD47 | RHCG | ENSP00000355361 | ENSP00000268122 | CD47 molecule; Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integr [...] | Rh family, C glycoprotein; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion | 0.610 |
| DNAH8 | AQP1 | ENSP00000333363 | ENSP00000311165 | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | aquaporin 1 (Colton blood group); Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.658 |
| DNAH8 | AQP2 | ENSP00000333363 | ENSP00000199280 | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | aquaporin 2 (collecting duct); Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient | 0.724 |
| DNAH8 | ATP6V0A4 | ENSP00000333363 | ENSP00000253856 | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | 0.738 |
| DNAH8 | RHCG | ENSP00000333363 | ENSP00000268122 | dynein, axonemal, heavy chain 8; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity) | Rh family, C glycoprotein; Functions as an electroneutral and bidirectional ammonium transporter. May regulate transepithelial ammonia secretion | 0.457 |
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