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STRINGSTRING
ATXN2L ATXN2L ENSG00000251569 ENSG00000251569 SPTA1 SPTA1 UBC UBC SRP68 SRP68 ABHD2 ABHD2 TBC1D2 TBC1D2 IVNS1ABP IVNS1ABP LGALS2 LGALS2 RAPH1 RAPH1 APBB1IP APBB1IP
"ABHD2" - abhydrolase domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ABHD2abhydrolase domain containing 2; May play a role in smooth muscle cells migration (By similarity) (425 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.883
LGALS2
lectin, galactoside-binding, soluble, 2; This protein binds beta-galactoside. Its physiological function is not yet known (132 aa)
            score_image   0.566
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1; Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion (1250 aa)
            score_image   0.555
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin- induced promoter activities through AP1 and SRE. Mediates Rap1- induced adhesion (666 aa)
            score_image   0.540
TBC1D2
TBC1 domain family, member 2 (917 aa)
            score_image   0.513
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2); Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane (2419 aa)
            score_image   0.503
IVNS1ABP
influenza virus NS1A binding protein (642 aa)
            score_image   0.485
SRP68
signal recognition particle 68kDa; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function (627 aa)
            score_image   0.481
ENSG00000251569
Bardet-Biedl syndrome 5 protein; Uncharacterized protein (544 aa)
            score_image   0.449
ATXN2L
ataxin 2-like (1097 aa)
            score_image   0.444
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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