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MRPL2 MRPL2 RPL9 RPL9 RPL11 RPL11 MRPS7 MRPS7 RPL5 RPL5 RPS3 RPS3 EFTUD1 EFTUD1 RPS2 RPS2 RPS5 RPS5 RPS15A RPS15A MRPS5 MRPS5
"EFTUD1" - elongation factor Tu GTP binding domain containing 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFTUD1elongation factor Tu GTP binding domain containing 1; Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits (1120 aa)    
Predicted Functional Partners:
RPL11
ribosomal protein L11; Binds to 5S ribosomal RNA (By similarity). Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML (By similarity) (178 aa)
score_image     score_image score_image   score_image   0.981
RPL5
ribosomal protein L5; Required for rRNA maturation and formation of the 60S ribosomal subunits. This protein binds 5S RNA (297 aa)
score_image     score_image score_image   score_image   0.980
RPS3
ribosomal protein S3 (243 aa)
score_image     score_image score_image   score_image   0.977
MRPS7
mitochondrial ribosomal protein S7 (242 aa)
score_image     score_image score_image   score_image   0.974
RPS5
ribosomal protein S5 (204 aa)
score_image     score_image score_image   score_image   0.974
RPS2
ribosomal protein S2 (293 aa)
score_image     score_image score_image   score_image   0.974
MRPS5
mitochondrial ribosomal protein S5 (430 aa)
score_image     score_image score_image   score_image   0.974
RPL9
ribosomal protein L9 (192 aa)
score_image     score_image score_image   score_image   0.973
RPS15A
ribosomal protein S15a (130 aa)
score_image     score_image score_image   score_image   0.972
MRPL2
mitochondrial ribosomal protein L2 (305 aa)
score_image     score_image score_image   score_image   0.970
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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