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STRINGSTRING
ENSG00000257767 ENSG00000257767 ALDH9A1 ALDH9A1 EHHADH EHHADH ALDH7A1 ALDH7A1 ALDH1B1 ALDH1B1 GAD2 GAD2 GAD1 GAD1 ABAT ABAT ALDH1A3 ALDH1A3 ALDH5A1 ALDH5A1 ALDH3A2 ALDH3A2
"ABAT" - 4-aminobutyrate aminotransferase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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protein homology
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Score
ABAT4-aminobutyrate aminotransferase; Catalyzes the conversion of gamma-aminobutyrate and L- beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine (500 aa)    
Predicted Functional Partners:
ALDH5A1
aldehyde dehydrogenase 5 family, member A1; Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) (548 aa)
score_image     score_image score_image score_image score_image   0.998
GAD1
glutamate decarboxylase 1 (brain, 67kDa); Catalyzes the production of GABA (594 aa)
score_image     score_image score_image score_image score_image   0.987
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Catalyzes the production of GABA (585 aa)
score_image     score_image score_image score_image score_image   0.985
ALDH9A1
aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
score_image     score_image score_image score_image score_image   0.949
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
      score_image   score_image score_image   0.949
ALDH1B1
aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (517 aa)
score_image     score_image score_image score_image score_image   0.947
ALDH3A2
aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (508 aa)
score_image     score_image score_image score_image score_image   0.946
ALDH7A1
aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
score_image     score_image score_image score_image score_image   0.945
ENSG00000257767
Uncharacterized protein (245 aa)
score_image     score_image score_image score_image score_image   0.943
ALDH1A3
aldehyde dehydrogenase 1 family, member A3; Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system (By similarity) (512 aa)
score_image     score_image score_image score_image score_image   0.943
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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