node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C10orf11 | LSM4 | ENSP00000361577 | ENSP00000469468 | chromosome 10 open reading frame 11 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA | 0.453 |
C10orf11 | LSM6 | ENSP00000361577 | ENSP00000296581 | chromosome 10 open reading frame 11 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5’-to-3’ mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing [...] | 0.837 |
C10orf11 | LSM7 | ENSP00000361577 | ENSP00000252622 | chromosome 10 open reading frame 11 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA and is probably a component of the spliceosome | 0.665 |
C10orf11 | PRPF6 | ENSP00000361577 | ENSP00000266079 | chromosome 10 open reading frame 11 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.826 |
C10orf11 | SART1 | ENSP00000361577 | ENSP00000310448 | chromosome 10 open reading frame 11 | squamous cell carcinoma antigen recognized by T cells; Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA | 0.861 |
C10orf11 | SNRPD2 | ENSP00000361577 | ENSP00000342374 | chromosome 10 open reading frame 11 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity) | 0.835 |
C10orf11 | SNRPD3 | ENSP00000361577 | ENSP00000215829 | chromosome 10 open reading frame 11 | small nuclear ribonucleoprotein D3 polypeptide 18kDa; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner | 0.853 |
C10orf11 | TXNL4B | ENSP00000361577 | ENSP00000268483 | chromosome 10 open reading frame 11 | thioredoxin-like 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition | 0.849 |
C10orf11 | ZMAT2 | ENSP00000361577 | ENSP00000274712 | chromosome 10 open reading frame 11 | zinc finger, matrin-type 2 | 0.818 |
LSM1 | LSM4 | ENSP00000310596 | ENSP00000469468 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA | 0.999 |
LSM1 | LSM6 | ENSP00000310596 | ENSP00000296581 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5’-to-3’ mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing [...] | 0.999 |
LSM1 | LSM7 | ENSP00000310596 | ENSP00000252622 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA and is probably a component of the spliceosome | 0.999 |
LSM1 | PRPF6 | ENSP00000310596 | ENSP00000266079 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.881 |
LSM1 | SART1 | ENSP00000310596 | ENSP00000310448 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | squamous cell carcinoma antigen recognized by T cells; Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA | 0.911 |
LSM1 | SNRPD2 | ENSP00000310596 | ENSP00000342374 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity) | 0.992 |
LSM1 | SNRPD3 | ENSP00000310596 | ENSP00000215829 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | small nuclear ribonucleoprotein D3 polypeptide 18kDa; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner | 0.982 |
LSM1 | TXNL4B | ENSP00000310596 | ENSP00000268483 | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | thioredoxin-like 4B; Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition | 0.789 |
LSM4 | C10orf11 | ENSP00000469468 | ENSP00000361577 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA | chromosome 10 open reading frame 11 | 0.453 |
LSM4 | LSM1 | ENSP00000469468 | ENSP00000310596 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA | LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Plays a role in replication-dependent histone mRNA degradation. Binds specifically to the 3’-terminal U-tract of U6 snRNA | 0.999 |
LSM4 | LSM6 | ENSP00000469468 | ENSP00000296581 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); Binds specifically to the 3’-terminal U-tract of U6 snRNA | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5’-to-3’ mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing [...] | 0.999 |