node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA8 | ABCB10 | ENSP00000269080 | ENSP00000355637 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family B (MDR/TAP), member 10; May mediate critical mitochondrial transport functions related to heme biosynthesis (By similarity) | 0.542 |
ABCA8 | ABCC2 | ENSP00000269080 | ENSP00000359478 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | 0.762 |
ABCA8 | ABCC9 | ENSP00000269080 | ENSP00000261200 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation | 0.512 |
ABCA8 | ABCD4 | ENSP00000269080 | ENSP00000349396 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm | 0.637 |
ABCA8 | ABCF1 | ENSP00000269080 | ENSP00000313603 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.650 |
ABCA8 | ABCF3 | ENSP00000269080 | ENSP00000411471 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family F (GCN20), member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B (By similarity) | 0.539 |
ABCA8 | ABCG2 | ENSP00000269080 | ENSP00000237612 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | ATP-binding cassette, sub-family G (WHITE), member 2 | 0.638 |
ABCA8 | SLC22A8 | ENSP00000269080 | ENSP00000337335 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | solute carrier family 22 (organic anion transporter), member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA) | 0.785 |
ABCA8 | SRRM1 | ENSP00000269080 | ENSP00000326261 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | serine/arginine repetitive matrix 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequen [...] | 0.607 |
ABCA8 | TNNI1 | ENSP00000269080 | ENSP00000337022 | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | troponin I type 1 (skeletal, slow) | 0.541 |
ABCB10 | ABCA8 | ENSP00000355637 | ENSP00000269080 | ATP-binding cassette, sub-family B (MDR/TAP), member 10; May mediate critical mitochondrial transport functions related to heme biosynthesis (By similarity) | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | 0.542 |
ABCC2 | ABCA8 | ENSP00000359478 | ENSP00000269080 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | 0.762 |
ABCC2 | ABCF1 | ENSP00000359478 | ENSP00000313603 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.507 |
ABCC2 | ABCF3 | ENSP00000359478 | ENSP00000411471 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | ATP-binding cassette, sub-family F (GCN20), member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B (By similarity) | 0.549 |
ABCC2 | ABCG2 | ENSP00000359478 | ENSP00000237612 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | ATP-binding cassette, sub-family G (WHITE), member 2 | 0.901 |
ABCC2 | SLC22A8 | ENSP00000359478 | ENSP00000337335 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | solute carrier family 22 (organic anion transporter), member 8; Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA) | 0.749 |
ABCC9 | ABCA8 | ENSP00000261200 | ENSP00000269080 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | 0.512 |
ABCC9 | ABCF1 | ENSP00000261200 | ENSP00000313603 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.535 |
ABCC9 | ABCF3 | ENSP00000261200 | ENSP00000411471 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation | ATP-binding cassette, sub-family F (GCN20), member 3; Displays an antiviral effect against flaviviruses such as west Nile virus (WNV) in the presence of OAS1B (By similarity) | 0.570 |
ABCD4 | ABCA8 | ENSP00000349396 | ENSP00000269080 | ATP-binding cassette, sub-family D (ALD), member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm | ATP-binding cassette, sub-family A (ABC1), member 8; ATP-dependent lipophilic drug transporter | 0.637 |